Noguchi Memorial Institute for Medical Research

Evaluation of the clinical performance of two new onchocerciasis rapid diagnostic tests in districts targeted for elimination in Ghana

Current diagnostic methods for onchocerciasis lack sufficient utility, sensitivity or specificity. Two new lateral flow assays developed by Bioaster and Global Access Diagnostics (BA/GADx) and Drugs and Diagnostics for Tropical Diseases (DDTD) multi-antigen test Biplex Version C...

Converging knowledges in the maternity ward in Ghana: an ethnographic study of care for women with pre-eclampsia

Efforts to improve maternal health rely heavily on biomedicine. Anthropologists, often US-based, have critiqued biomedicine for being 'authoritative knowledge' that shifts power from women to medical experts, and colonises and de-values other birth traditions. However, this ethno...

A Methodological Framework for Panel-Data Estimation of Maintenance Depot System Adoption in Ghana, 2000–2026

The adoption of systematic maintenance depot systems is critical for transport infrastructure sustainability in developing nations. However, methodological limitations in measuring longitudinal adoption rates hinder effective policy evaluation and resource allocation. This articl...

A Methodological Framework for Panel-Data Estimation of Maintenance Depot System Adoption in Ghana, 2000–2026

The adoption of systematic maintenance depot systems is critical for transport infrastructure sustainability in developing nations. However, methodological limitations in measuring longitudinal adoption rates hinder effective policy evaluation and resource allocation. This articl...

A Bayesian Hierarchical Modelling Approach to the Cost-Effectiveness of Community-Based Health Systems in Ghana

{ "background": "Community-based health systems are a cornerstone of primary care in many African nations, yet robust, context-specific evaluations of their cost-effectiveness remain scarce. Existing analyses often fail to adequately account for hierarchical data structures and t...

Epidemiology of the hepatitis delta virus (HDV) in West Africa: a systematic review

Background Hepatitis delta virus (HDV) represents the most severe form of chronic viral hepatitis yet remains neglected in resource-limited settings. West Africa, with high hepatitis B virus (HBV) endemicity and unique sociocultural risk factors, represents a critical region for...

A Bayesian Hierarchical Modelling Approach to the Cost-Effectiveness of Community-Based Health Systems in Ghana

{ "background": "Community-based health systems are a cornerstone of primary care in many African nations, yet robust, context-specific evaluations of their cost-effectiveness remain scarce. Existing analyses often fail to adequately account for hierarchical data structures and t...

Progress towards Onchocerciasis elimination in Senegal’s historical transmission zones, following sustained annual mass drug administration and multilevel surveillance

Onchocerciasis remains a major public health problem in sub-Saharan Africa, despite decades of control efforts. In Senegal, transmission was historically focal but intense along the Gambia and Falémé river basins in the southeast of the country. Building on the legacy of the Onch...