New York Medical College

Attitude and Medical Knowledge Among Medical Trainees and Physicians on the Transgender Population: A Multi-Institutional Survey

Objectives Despite a growing population of people who identify as transgender in the United States, existing healthcare and medical education systems have not all adapted to meet the needs of transgender people. Transgender individuals face persistent disparities in accessing hea...

Obesity and morbid obesity are associated with reductions in live birth rate and increased miscarriage rate after frozen embryo transfer

Abstract Purpose Obesity is associated with poor in-vitro fertilization (IVF) outcomes, with limited data on patients with BMI ≥ 40 kg/m 2 . This study assessed BMI’s impact on frozen embryo transfer (FET) outcomes. Methods A retrospective cohort study (2017–2024) of 1,424 FETs f...

Hypertension Management in Breastfeeding Patients: Balancing Maternal Blood Pressure Control and Infant Safety

Hypertension is a leading cause of death and disability in the United States, affecting nearly half of all Americans, according to the NIH. Postpartum hypertension is a clinically important form of hypertension that can be preexisting or arise during or after pregnancy. While the...

Long Non-Coding RNA LINC01614 Promotes Aggressive Phenotypes and Ferroptosis Resistance in Papillary Thyroid Cancer Through a Putative miR-4521/IGF2/PI3K-AKT Signaling Axis

Background/Objectives: Papillary thyroid cancer (PTC) is the most common endocrine malignancy and is generally associated with favorable clinical outcomes. However, a subset of tumors develops aggressive phenotypes characterized by increased proliferation, migration, therapeutic...

Optimizing combinatorial macrophage induced innate immunotherapy against Ewing sarcoma

Abstract Background We previously reported that Ewing sarcoma (ES), a pediatric bone and soft tissue tumor, escapes macrophage phagocytosis by upregulating the CD47 “don’t eat me” signal and downregulating the cell-surface calreticulin (csCRT) “eat me” signal. Targeting this dual...

Rethinking Restrictive Diets in IBD: Toward an Inclusion-Focused Nutritional Paradigm

Abstract Purpose of Review Patient-initiated elimination diets are widely adopted by those with inflammatory bowel disease (IBD), yet the evidence supporting their long-term use remains limited and their risks are increasingly recognized. Some common elimination diets utilized by...

Intravascular Lithotripsy for Calcified Vascular Lesions: Mechanisms, Techniques, Clinical Applications, and Future Directions

Vascular calcification complicates endovascular intervention by reducing vessel compliance, impairing device delivery and expansion, and increasing the risk of suboptimal procedural outcomes. Intravascular lithotripsy (IVL) has emerged as a calcium-modification strategy that uses...

Non-Invasive Skin Imaging Techniques for Diagnosing and Monitoring Mycosis Fungoides: A Comprehensive Review

Mycosis fungoides, the most common primary cutaneous T-cell lymphoma, presents notable diagnostic challenges. In its early stages, it may resemble inflammatory dermatoses both clinically and histologically, causing delays in diagnosis. These factors can lead to treatment delays,...

Cardiometabolic Risk Reduction Through Selective Amylin Receptor Agonism

Obesity remains a major modifiable driver of cardiovascular disease. Emerging antiobesity pharmacotherapies demonstrate substantial weight loss alongside improvements in multiple cardiometabolic parameters. This literature review summarizes the early clinical studies of eloralint...

Clinical trial barriers in neurostimulation for pediatric drug‐resistant epilepsy

Abstract Objective The NeuroPace responsive neurostimulation (RNS) System effectively treats focal drug‐resistant epilepsy (DRE) in adults but lacks pediatric regulatory approval. Despite effective off‐label pediatric use, systemic device‐trial challenges have impeded label expan...

Minimal-length CAG repeats in AR define a hyperactive AR–LSD1 axis driving metabolic reprogramming in prostate cancer

The polymorphic CAG trinucleotide repeat in the androgen receptor ( AR ) gene encodes a variable-length N-terminal polyglutamine (polyQ) tract that modulates AR transcriptional activity, with shorter tracts generally enhancing AR activity. While the majority of men harbor CAG rep...

Management of Patent Ductus Arteriosus in the Adult Population

Patent ductus arteriosus (PDA) is defined as a persistent communication between the pulmonary artery and the aorta that normally closes before birth. While the ductus arteriosus is an essential vascular shunt for a developing fetus, its failure to close can become pathologic. Mos...

Left Atrial Strain Impairment in Embolic Stroke of Undetermined Source: A Systematic Review and Meta-Analysis

Embolic stroke of undetermined source (ESUS) accounts for approximately one-third of all ischemic strokes. Atrial cardiomyopathy, independent of paroxysmal atrial fibrillation, is an increasingly recognized embolic substrate. Left atrial (LA) strain assessed by speckle-tracking e...

Inpatient outcomes after acute ischemic stroke in patients with leukemia: A retrospective observational cohort study

Abstract: INTRODUCTION: Leukemia is associated with a greater risk of stroke due to increased hypercoagulability and introduction of treatment modalities that increase the risk of thrombosis. METHODS: Using the 2015–2022 National Inpatient Sample database, a retrospective observa...

Microvascular Diseases of the Eye: Retinal Vasculature as a Cardiometabolic Biomarker

Microvascular disease of the eye encompasses both structural and functional changes to the retinal vessels. Cardiometabolic disorders, such as hypertension and diabetes, are associated with early, measurable abnormalities in the retinal microvascular network that often emerge bef...

Timing and Incidence of Airway Interventions Following Occipitocervical Fusion: A Retrospective Study Using the Nationwide Inpatient Sample 2017 to 2022

Background: Occipitocervical fusions (OCFs) are associated with adverse airway events. The period of airway compromise remains poorly defined. The objective of this study was to identify differences between OCF and posterior cervical fusion not involving the occipitocervical join...

Menopausal Hormone Therapy and Cardiovascular Risk: Current Evidence and Treatment Recommendations

In 2025, the US Food and Drug Administration (FDA) removed its prior class-wide boxed warnings for menopausal hormone therapy (MHT), paving the way for increased clinical use. Menopause accelerates cardiovascular risk independently of chronological aging, manifesting as a 7.5% in...

Berberine Inhibits Eczematous Skin S. aureus-Induced Mast Cell/Basophil Activation and Modulates MAPK-Associated Gene Expression

Staphylococcus aureus (S. aureus), a primary exacerbating factor in eczema, remains a prevalent pathogenic public-health threat. The mechanism of mast cell/basophil degranulation in the context of S. aureus-exacerbated eczema remains unclear. We sought to investigate the direct e...

The History of Neurosurgery at New York Medical College and Westchester Medical Center

The history of the Department of Neurosurgery at the New York Medical College (NYMC) began in New York City in the early 20th century. The purpose of this manuscript is to educate on the history of neurosurgery at NYMC and Westchester Medical Center (WMC) from its early beginning...

Three-Dimensional Bioprinting in Reconstructive Plastic Surgery: A Comprehensive Review

Three-dimensional (3D) bioprinting is an evolving biofabrication approach in regenerative medicine with the potential to overcome many limitations of conventional reconstructive techniques, including donor-site morbidity, limited tissue availability, and suboptimal restoration of...