National Yang Ming Chiao Tung University

Fullerene‐Mediated Iodine Immobilization at Buried Interfaces in Sn–Pb Perovskite Solar Cells

ABSTRACT Narrow‐bandgap perovskite solar cells (PSCs) are promising absorbers for tandem photovoltaics; however, their performance remains limited by interfacial recombination and instability, particularly Sn 2+ oxidation and halide‐related degradation. Although fullerene derivat...

A Preliminary Evaluation of 177Lu-PSMA-617-Based Targeted Radioligand Therapy with X-Ray Stimulated PSMA Relocation Using the PiggyBac Reporter-Gene-Engineered Orthotopic Prostate Tumor Model

Background/Objectives: Because human prostate cancer (PCa) typically exhibits slow tumor growth, establishing reliable PCa tumor models is often time-consuming and unpredictable, thereby limiting the efficiency of preclinical theranostic research. To overcome this limitation, thi...

TogoPhosTAC as a delivery-ready platform for targeted protein dephosphorylation

Phosphorylation-targeting chimeras (PhosTACs) enable targeted protein dephosphorylation by recruiting phosphatases through induced proximity. However, the direct recruitment of phosphatase subunits or holoenzymes with small molecules remains challenging, as suitable ligands are s...

Algorithmic Prognostication in Female Oncofertility Counseling: Ethical Challenges of Bias, Autonomy, and Predictive Uncertainty

Advances in machine learning, predictive analytics, and clinical prediction modeling have accelerated the development of algorithmic tools for estimating reproductive outcomes after cancer treatment. In female oncofertility counseling, these models may support individualized asse...

Potential Risks of Virtual Influencer Diversity in Charitable Endorsements: A Cognitive Dissonance Perspective

ABSTRACT Highlighting diversity‐related attributes has become an increasingly prominent marketing communication strategy in virtual influencer endorsement practices. Prior research has largely focused on commercial endorsement contexts, conceptualized diversity as a homogeneous a...

A population-specific genomic reference panel for Taiwan: NHRI-RP-1

Abstract Background To enhance the efficiency of identifying rare variants within the Taiwanese population and to support genome-wide association studies (GWAS) and imputation studies for genetic risk prediction in the Han population, we have developed the National Health Researc...

Beyond the “Benign” Label: Toward Phenotype-Specific Risk Stratification in Apical Hypertrophic Cardiomyopathy

Apical hypertrophic cardiomyopathy (HCM) was first described nearly 5 decades ago by Yamaguchi and colleagues 1) in a Japanese cohort, characterized by giant T-wave inversion and the now-iconic "ace-of-spades" left ventricular morphology, and reported at the time with strikingly...

Solving the Gross-Pitaevskii equation with quantic tensor trains: Ground states and nonlinear dynamics

We develop a tensor network framework based on the quantic tensor train (QTT) format to efficiently solve the Gross-Pitaevskii equation (GPE), which governs Bose-Einstein condensates under mean-field theory. For sufficiently regular functions, the QTT approach enables exponential...

Optimizing Recovery in Head and Neck Surgery: Factors Influencing Drainage and Early Discharge

Background: Postoperative bleeding and prolonged drainage after head and neck surgery may delay drainage tube removal and hospital discharge, increasing complication risk and resource utilization. Optimizing intra and postoperative hemostasis is essential to facilitate early reco...

The efficacy and safety of monthly intravenous methylprednisolone pulse therapy in Taiwanese alopecia areata patients: A retrospective cohort study

Abstract Background: Intravenous methylprednisolone pulse (IVMP) therapy has been widely used for treating severe or recalcitrant alopecia areata (AA), but treatment protocols and efficacy vary. Objectives: This study aims to evaluate the efficacy of IVMP, identify predictive fac...

Risk of Dementia after initiation of GLP-1 RA versus long-acting insulin in patients with type 2 Diabetes mellitus

Background Recent studies suggest a decreased risk of dementia in patients treated with glucagon-like peptide-1 receptor agonist (GLP-1 RA). In this study, we compare the risk of dementia associated with GLP-1 RA versus long-acting insulin in adults aged over 50 years with type 2...

Tailoring Trilayer LiTa 2 PO 8 ‐Based Hybrid Solid Electrolytes to Enhance Interfacial Compatibility and Efficient Lithium Transport in Lithium Metal Batteries

ABSTRACT Herein, a spatially decoupled trilayer hybrid solid electrolyte (THSE) is designed through functional architecture engineering to simultaneously optimize ionic conduction and interfacial stability. THSE integrates a polymer matrix comprising a Li + ‐conductive LiTa 2 PO...

Magneto-Electronically Coupled Quasiparticle Statesin Monolayered MoS2 Driven by the Proximity Effect of UltrathinSmFeO3

Abstract The magnetic proximity effect (MPE) of magnetic substrates provides an effective route to manipulate spin/valley-dependent quasiparticles in two-dimensional transition-metal dichalcogenides (TMDs) without requiring large external magnetic fields. Herein, we demonstrate a...

Agitation in dementia: Evidence-based consensus recommendations

Agitation is among the most disabling behavioral and psychological symptoms of dementia, contributing substantially to caregiver burden, institutionalization, and healthcare utilization. Considering the modest efficacy and significant adverse effects associated with psychotropic...

Flexible MultimodalNeural Probe with Integrated Three-ElectrodeAptameric Sensing for In Vivo Monitoring of DopamineDynamics and Neural Activity

Abstract Neural function emerges from the interplay between electrical activity and neurochemical signaling, yet most implantable neural interfaces primarily record electrophysiological signals and lack molecular specificity for neurotransmitter monitoring. Here, we developed a f...

Tetraniline-Engineered Nickel Molecular Frameworks for Combinatorial NIR-Triggered Photothermal and Photodynamic Cancer Therapy

Near-infrared (NIR)-responsive nanomaterials are of critical importance for biomedical applications owing to their superior tissue penetration depths. Herein, we present a rational design of NIR-responsive tetraniline (TANI)-engineered nickel coordination frameworks for multimoda...

A Novel Titanium End-Disc-Assisted Allograft Preparation System for Anterior Cervical Corpectomy and Fusion: Development and Preliminary Biomechanical Evaluation

Background: Allograft bone remains an attractive option for anterior cervical corpectomy and fusion (ACCF), but its use can be limited by variable graft geometry, insufficient endplate contact, and operator-dependent trimming. This study aimed to develop a titanium end-disc-assis...

Low‐intensity focused ultrasound neuromodulation for drug‐resistant epilepsy: A randomized, sham‐controlled crossover trial

Abstract Objective This study was undertaken to evaluate the safety, feasibility, and efficacy of low‐intensity focused ultrasound (LIFU) as a noninvasive neuromodulation technique in patients with drug‐resistant epilepsy (DRE). Methods In this pilot, single‐blind, randomized sha...

Adipose Tissue Browning in MASLD and Its Molecular Mechanisms and Metabolic Crosstalk

PURPOSE OF REVIEW: Metabolic dysfunction-associated steatotic liver disease (MASLD) is an increasingly prevalent complication of obesity and metabolic dysregulation, with limited therapies targeting upstream drivers of disease. Adipose tissue has emerged as a central regulator of...

The experience of cross-setting care transitions of long-term care residents to the emergency department: a qualitative study

As the population ages, the medical needs of residents in long-term care (LTC) facilities are increasing. However, there remains a lack of in-depth exploration of how clinical information and care responsibilities are understood and transferred across settings when LTC residents...