National Yang Ming Chiao Tung University

Green Synthesized WO3-PEDOT:PSS Composites into Benzoid-Rich Conformation for Nonenzymatic Bioelectronic Tongues for Tannic Acid-Based Wine Astringency Detection

Abstract This study introduces electrochemical sensor materials based on a conductive polymer PEDOT:PSS and a green-synthesized WO3 electrode (i.e., polymer composites of PEDOT:PSS@WO3-n, where n = 1–3 with three wt. ratios of PEDOT:PSS/WO3 = 1/1, 1/2, and 1/3, respectively) to d...

Multi-Locus Molecular Findings in Pediatric-Onset Inherited Metabolic Disorders: An Eight-Year Series of Outsourced Genomic Testing in Taiwan

Background/Objectives: Outsourced genomic testing can identify additional findings in patients with inherited metabolic disorders (IEMs), including lysosomal storage diseases. We examined these findings in a selected Taiwanese series. Methods: We retrospectively reviewed 13 patie...

Artificial Grain Boundaries Created by Freestanding Membrane Transfer Reveal Angle‐Dependent Ferroelectric Switching and Leakage in BaTiO 3

ABSTRACT Grain boundaries (GBs) strongly influence polycrystalline ferroelectrics, but their discrete effects are difficult to isolate because of nanoscale heterogeneity. Here, we use freestanding membrane transfer to fabricate artificial GBs with controlled, experimentally acces...

Coordination‐Asymmetry‐Regulated Reconstruction of Electron‐Rich Cu Sites for pH‐Dependent Nitrate‐to‐Ammonia Electrocatalysis

ABSTRACT Electrocatalytic nitrate reduction reaction ( e‐ NO 3 RR) offers a promising route to valorize nitrate‐contaminated wastewater while enabling sustainable ammonia production; however, how local coordination asymmetry regulates Cu‐site evolution and reaction pathways acros...

Nonselective beta-blockers and hepatic encephalopathy in liver cirrhosis:A meta-analysis of randomized controlled trials

BACKGROUND: Liver cirrhosis leads to portal hypertension and related complications, including ascites, esophageal varices, and hepatic encephalopathy (HE). Non-selective beta blockers (NSBBs) decrease portal pressure, but it is not yet clear whether they contribute to HE developm...

Machine Learning on Heterogeneous, Edge, and Quantum Hardware for Particle Physics

The next generation of particle physics experiments will face an era of challenges in data acquisition, due to unprecedented data rates and volumes along with extreme environments and operational constraints. Harnessing these data for scientific discovery demands real-time infere...

Dimensional Engineering of Co/W Superlattices Enables Out-of-Plane Spin Polarization with 90% Field-Free Switching in Perpendicular CoFeB

Abstract Deterministic spin–orbit torque (SOT) switching of perpendicular magnets without external magnetic fields remains a central challenge for scalable SOT-MRAM. Here, we demonstrate that dimensional engineering of a Co/W superlattice spin–orbit layer enables >90% field-free...

Interventricular septal thickness for cardiomyopathic phenotype enrichment in patients with established left ventricular hypertrophy

We evaluated whether interventricular septal thickness in diastole (IVSd) ≥ 15 mm enriches cardiomyopathic phenotypes among adults with established left ventricular hypertrophy (LVH) and whether broader clinical-echocardiographic features improve triage. We studied 1,127 adults u...

Understanding ongoing processes of terrestrial mud diapirism through absolute gravimetry and geodetic approaches in SW Taiwan: implications for geological hazards

Mud diapirs and mud volcanoes are widespread geological features driven by subsurface seepage or extrusion of liquid and over-pressured mudstone. These formations pose significant hazards due to the emission of flammable gases, formation of mudflows, and release of atmospheric me...

Driving mechanisms of a new SVR-based trend anomaly in China’s A-share market

This paper constructs a multi-horizon trend signal using support vector regression trained on short-, medium-, and long-term moving averages to capture asynchronous trading behaviours of heterogeneous investors. Long-short portfolios sorted on the trend signal yield significant r...

Using machine learning and preoperative data to predict 30-day mortality after non-cardiac major surgeries in older patients

Postoperative mortality remains a critical concern, especially among older patients undergoing non-cardiac major surgeries. With over 300 million surgeries performed worldwide annually, a significant proportion involves elderly patients, making early and precise risk stratificati...

Integrating generative artificial intelligence facilitates faculty interaction network and role transition in a biostatistics curriculum

In a two-year action-research study within an undergraduate biostatistics curriculum for nursing, pharmacy, and medical biotechnology students, we examined how generative artificial intelligence (GenAI) facilitates educators to design, supervise, and evaluate learning. Students u...

Rational Control of Antibody Orientation for Enhancing Sensitivity and Specificity in Lateral Flow Immunoassays With Clinical Validation

Lateral flow assays (LFAs) are widely used for point-of-care diagnostics, but their sensitivity is often limited by inefficient antibody orientation and poor signal transduction. Herein, we report a universal strategy integrating orientation-controlled antibody conjugation at the...

Nanoamphizymes: Self‐Assembled Amphiphilic Enzymatic Nanomaterials for High‐Performance Biocatalysis and Biosensing

ABSTRACT Nanomaterials offer versatile platforms for biocatalysis by modulating enzyme stability and activity at the nano–bio interface. However, strong interfacial interactions often disrupt enzyme structure and cause substantial activity loss, while the largely empirical nature...

Clinical Implications of the Novel Genetic Polymorphism Associated With Retinal Vein Occlusion: The East Asian GWAS Survey in a Single-Center Taiwanese Cohort

Purpose: To explore the single-nucleotide polymorphic features in an East Asian cohort of retinal venous occlusion (RVO) patients, to map pathogenic genes, and to analyze potential pathophysiological associations. Methods: This was a cross-sectional monocentric cohort study invol...

Comparative Gas-Sensing Studies of EPAA with Aniline Tetramer in the Main/Side Chain and Corresponding Densely/Porous Electro-Spun Films

Rapid low-ppm detection of toxic and corrosive hydrogen sulfide (H2S) is essential to protect workers and the public. This research presents the synthesis and gas-sensing application of two electroactive poly(amic acid)s (EPAAs): a linear-type (L-EPAA) and a branched-type (B-EPAA...

Laser-Induced Graphene Microarrays for Enhanced Quantitative Precision in Surface-Assisted Laser Desorption/Ionization Mass Spectrometry

Abstract Laser desorption/ionization mass spectrometry offers distinct advantages for biomolecular analysis owing to its high salt tolerance, low sample consumption, and soft ionization capability. However, localized laser−sample interactions are inherently affected by heterogene...

SrZrO3 Polyhedra with Lattice Variations Showing Efficient Piezocatalytic Hydrogen Evolution

Abstract SrZrO3 cubes with two different sizes as well as octahedra and rhombic dodecahedra have been solvothermally synthesized. Synchrotron X-ray diffraction (XRD) analysis indicates the possession of an orthorhombic crystal structure, with cubes and octahedra having greater ce...

Treatment of distal femoral malignant bone tumors with freezing tank–assisted pedicle-freezing: a retrospective study of 31 patients

Biological reconstruction with recycled autografts is an established option for limb salvage after bone tumor resection, but complications such as graft failure and nonunion remain concerns. Pedicle freezing was introduced in 2010 and showed potential in reducing nonunion. Howeve...

Semi-analytical modeling and experimental measurement of elastic thermal expansion and aspect-ratio effects in Cu/SiO2 vias for 3D IC integration

Thermally induced protrusion of Cu pads embedded in SiO 2 vias is important for fine-pitch Cu/SiO 2 hybrid bonding, but its dependence on via geometry remains incompletely quantified. In this work, in situ heating atomic force microscopy (AFM) measurements at 25 and 200 °C are co...