National Institute on Aging

The interplay of air pollution with plasma neurodegenerative markers and metabolome for dementia, Parkinson’s disease and all-cause mortality risks and transitions: The UK Biobank study

We investigated the joint associations of circulating neurodegeneration markers—neurofilament light (NfL) and glial fibrillary acidic protein (GFAP)—ambient air pollution, and plasma metabolomic profiles with transitions from a healthy state to dementia, Parkinson’s disease (PD),...

Association Between Changes in Perceived Neighborhood and Cognitive Performance Within Healthy Aging in Neighborhoods of Diversity Across the Life Span (HANDLS) Black Adults

Perceived neighborhood characteristics are related to cognitive performance. However, limited studies have examined how changes in neighborhood characteristics relate to cognitive performance, particularly among Black adults who are likely to experience changes in their residenti...

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

ABSTRACT Objective Susac syndrome (SS) is a rare CD8 + T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteom...

Association between self-reported oral health issues and autoimmune diseases: evidence from UK biobank

Oral microbiome dysbiosis may contribute to autoimmune disease development, but epidemiological evidence linking oral health and autoimmune disease risk is limited. To evaluate the association between self-reported oral health issues by questionnaire—defined as the presence of pa...