National Guard Health Affairs

The clinical presentation and outcomes of dengue fever: a review of a tertiary care center in Saudi Arabia

Dengue fever (DF) is a viral infection spread by mosquitoes and is one of the most frequently reported infectious diseases in Saudi Arabia, particularly in Jeddah. Despite recurring outbreaks, recent data on the clinical characteristics, seasonal variation, and outcomes of affect...

Pregabalin-associated adverse drug reactions

Pregabalin is widely used for neuropathic pain, epilepsy, and anxiety disorders but has become increasingly associated with misuse and dependence. Understanding its global safety profile is essential to support pharmacovigilance and toxicovigilance efforts. This study aimed to ch...

Exploring the Link: A Study on Consanguinity and Orofacial Clefts

Objective To evaluate the association between parental consanguinity and cleft phenotype, family history, syndromic status, regional distribution, and sex-specific presentation among Saudi patients affected by cleft lip and/or palate (CL/P). Design Retrospective cross-sectional o...

Protecting the Recurrent Laryngeal Nerve During Esophagectomy: Clinical Impact of Intraoperative Neurophysiological Monitoring

Recurrent laryngeal nerve (RLN) injury remains one of the most consequential complications of esophagectomy, driving vocal cord palsy, aspiration, and pneumonia. Monitoring techniques, signal interpretation, and the underlying clinical evidence for intraoperative neurophysiologic...

Protecting the Recurrent Laryngeal Nerve During Esophagectomy: Clinical Impact of Intraoperative Neurophysiological Monitoring

Recurrent laryngeal nerve (RLN) injury remains one of the most consequential complications of esophagectomy, driving vocal cord palsy, aspiration, and pneumonia. Monitoring techniques, signal interpretation, and the underlying clinical evidence for intraoperative neurophysiologic...

National Trends in Gender Representation, Segregation, and Disparities in the Saudi Dental Workforce, 2016–2025

Introduction and aims Despite the importance of gender equity for promoting fairness and informing workforce planning, key indicators of gender equity in the Saudi dental workforce remain underexplored. This study assessed gender representation in the Saudi dental workforce from...

Cross-cultural adaptation of cancer health literacy instruments in Arabic: the CHLT-30-Arabic and CHLT-6-Arabic

Background Health literacy plays a crucial role in physical and mental health outcomes. Patients with chronic diseases, cancer patients in particular, shoulder a disproportionate burden due to limited health literacy. Limited cancer health literacy (LCHL) is a risk factor for dis...

Sphenoid fungal rhinosinusitis across the disease spectrum: a case series of non-invasive fungal ball and fatal acute invasive fungal rhinosinusitis

Introduction: Sphenoid fungal rhinosinusitis is an uncommon but clinically important entity ranging from non-invasive fungal ball to rapidly fatal acute invasive fungal rhinosinusitis. Case presentation: We report two contrasting cases of sphenoid fungal disease. The first was a...

Children With Synpolydactyly Type I Homozygous HOXD13 Mutations: Embryology and Surgical Correction of the “Cupping” of the Hands and Feet

PURPOSE: Some patients with familial Synpolydactyly Type I have severe flexion deformities of the hands and feet at the metacarpophalangeal and the metatarsophalangeal joints, and the resulting deformity has been named "cupping" of the hands and feet. Severe "cupping" requiring s...

Role of consolidative surgery after chemotherapy in recurrent/metastatic adrenal cortical cancer (ACC): Princess Margaret Cancer Centre experience

Recurrent/Metastatic (R/M) ACC is aggressive with few effective treatment options. The role of surgery after chemotherapy remains unclear. Moreover, prognostic factors in R/M ACC are not well defined. R/M ACC patients treated at Princess Margaret Cancer Centre (2002–2019) were re...