Naresuan University

Risk factors for syphilis among newly admitted prisoners: A case–control study

Background Syphilis remains a major global public health concern in various groups, including people in prisons, where the burden is substantial. This study aimed to identify factors associated with syphilis infection among newly admitted prisoners in a province of Thailand. Meth...

Performance Assessment of Centrifugation-Based Hematocrit Testing in Primary Care Units: Evidence from Seventy-Two Proficiency Testing Datasets over Eight Years

Background: Centrifugation-based hematocrit (Hct) testing remains widely used in decentralized primary care settings where access to automated hematology analyzers may be limited. Appropriate proficiency testing (PT) performance assessment therefore requires consideration of the...

Systematic review of eyecare Patient-Reported Experience Measures (PREMs) following COSMIN guidelines

Abstract Patient-Reported Experience Measures (PREMs) are essential for assessing healthcare quality from the patient’s perspective. However, their use in eyecare is limited. This systematic review aimed to assess the existing evidence on the measurement properties of PREMs used...

Cost-effectiveness and budget impact of Luspatercept in Thai adults with transfusion-dependent beta-thalassaemia: a multi-state Markov model based on national claims data

Background Luspatercept is a first-in-class erythroid maturation agent that reduces transfusion burden in adults with transfusion-dependent beta-thalassaemia (TDT). However, its cost-effectiveness has not been evaluated in middle-income settings. This study aimed to evaluate the...

Bioinspired Suction-Cup Architecture Modulates Hydration and Pomegranate-Extract Release from NVP/HEMA/CMC Hydrogels

Surface architecture may tune hydrogel transport without changing formulation. Flat and suction-cup N-vinylpyrrolidone/2-hydroxyethyl methacrylate/carboxymethyl cellulose (NVP/HEMA/CMC) hydrogels prepared from the same nominal formulation were compared for hydration, equilibrium...

Improving the Efficiency of Synthesis and Demonstrating the Utility of Difunctionalized Tris-Cyclometallated Iridium Intermediates

Two key reactions in the synthesis of a difunctionalized tris-cyclometallated iridium complex [Ir(ppy-Br)2fppy] (3), which is an important intermediate for the synthesis of more sophisticated iridium complexes, were investigated to improve performance. The first reaction is the f...

Development and evaluation of a novel artificial saliva for xerostomia: physicochemical, microbial, and safety profiles

Xerostomia significantly impairs oral function and quality of life. Existing artificial saliva formulations often exhibit acidic pH or rely on synthetic preservatives such as parabens, which may limit their suitability for long-term use. This study aimed to develop a pH-neutral a...

Topical tissue adhesive versus subcuticular suturing in minimally invasive spine surgery a randomized paired incision trial

Abstract Skin closure technique may influence wound healing, cosmetic outcomes, and operative efficiency in minimally invasive spine surgery (MISS). This prospective assessor- and patient-blinded randomized controlled trial compared topical tissue adhesive with subcuticular sutur...

Chemopreventive effect of arachidin-rich extract from peanut hairy root cultures on inflammation-induced cholangiocarcinogenesis in a cytokine-treated biliary cell model

Cholangiocarcinoma (CCA) is a highly prevalent malignancy in Southeast Asia and is strongly associated with chronic biliary inflammation. Preventive strategies targeting early inflammation-driven carcinogenic events are therefore of great interest. Arachidin-rich extracts derived...

Anti-Inflammatory Effects of Artocarpin-Loaded Chitosan Microparticles on Inflammatory Chondrocytes

Artocarpin is a promising bioactive compound with anti-inflammatory potential; however, its limited aqueous solubility may restrict its direct biological application. Therefore, artocarpin-loaded chitosan microparticles (CSPs/AE) were prepared as a biocompatible carrier to improv...

Curcuma longa nano-emulsions against bovine mastitis inducing bacteria: Machine-learning based optimization and characterization

Abstract This study examined the physicochemical characteristics, antibacterial activity, and anti-biofilm efficacy of Curcuma longa nano-emulsions formulated using a lactic acid–menthol–based hydrophobic deep eutectic solvent as the oil phase and Tween 80–propylene glycol or Twe...

Coarse-graining analysis for non-invasive, label-free, and quantitative evaluation of undulating motion in cultured oral mucosa epithelial cell sheets

Background Cultured oral mucosa epithelial cell sheets (COMECS) represent a promising therapeutic approach for epithelial repair, such as corneal reconstruction or esophageal mucosa defects; however, current quality assessment methods are largely invasive and destructive. Althoug...

Epithelial integration in tissue-engineered oral mucosa using RGDTFI-presenting micropatterned collagen scaffolds

Objective To determine whether presentation of the integrin αvβ3/αvβ5-binding peptide motif RGDTFI on micropatterned collagen scaffolds improves epithelial coverage and stabilizes the epithelial–scaffold interface during fabrication of tissue-engineered oral mucosa (TEOM). Method...

Percutaneous transvenous mitral commissurotomy during pregnancy: a contemporary Southeast Asian experience

Abstract Background Severe rheumatic mitral stenosis during pregnancy is associated with substantial maternal and fetal morbidity because physiological hemodynamic changes may precipitate heart failure and pulmonary hypertension. Percutaneous transvenous mitral commissurotomy (PT...

Effectiveness of probiotic supplementation in reducing halitosis among older adults: a randomized, double-blind, placebo-controlled crossover trial

Halitosis is a common oral health condition among older adults and is primarily associated with volatile sulfur compounds (VSCs) produced by oral bacteria. Probiotics have been proposed as a potential approach to modulate oral microbiota and reduce halitosis. This study aimed to...

Phenotypic and Genomic Analysis of Swine-Derived Bacillus subtilis 1BP1Co1 as a Functional Probiotic Candidate to Mitigate Escherichia coli-Associated Diarrhea

Post-weaning diarrhea caused by pathogenic Escherichia coli is a significant economic challenge in global swine production. Rising antimicrobial resistance linked to traditional antibiotics necessitates safe, sustainable alternatives. This study isolated and characterized host-as...

Prediction model for abnormal joint line obliquity after open wedge high tibial osteotomy using knee radiographic parameters

Abstract Background The purpose of this study was to identify key preoperative radiographic parameters and develop a predictive model for abnormal knee joint line obliquity (KJLO) following medial open-wedge high tibial osteotomy (MOWHTO) in patients with medial compartment knee...

Organization of the Digestive Tract and Localization of Protein Fibre in Electrophorus sp. (Gymnotiformes: Gymnotidae)

ABSTRACT Research into the electric eel ( Electrophorus ) has focused on its production of high‐voltage electrical discharges for predation and defence, and its divergence from other fish species in terms of molecular activities. However, the knowledge of its digestive biology re...