Nantes Université

A composite, host‐participatory haustorium links host compatibility to defence bifurcation in Alectra vogelii (Orobanchaceae)

Societal Impact Statement Parasitic weeds of the family Orobanchaceae are among the most damaging constraints on food production in the tropics, draining water and nutrients from their hosts and threatening the livelihoods of millions of smallholder farmers. Yellow witchweed ( Al...

Autoimmune and inflammatory diseases associated with T-cell clonal expansion

Autoimmune and inflammatory diseases (AID) result from a breakdown of immune tolerance, often driven by T-cell dysregulation and sometimes associated with clonal T-cell expansion. While T-cell large granular lymphocyte leukemia (LGL-L) is a well-defined clonal disorder commonly a...

Assessment of infection prevention practices in office-based surgery: a multicentre regional audit

Abstract Background Office-based surgery (OBS) is increasingly used due to organizational constraints and perceived benefits. However, data on infection prevention and control (IPC) practices in OBS settings remain limited. This study aimed to assess the conditions in which OBS a...

MAIA frailty subgroup analysis: long-term follow-up with daratumumab plus lenalidomide/dexamethasone in transplant-ineligible newly diagnosed myeloma

Abstract In MAIA (Daratumumab, lenalidomide, and dexamethasone versus lenalidomide and dexamethasone alone in newly diagnosed multiple myeloma), daratumumab plus lenalidomide/dexamethasone (D-Rd) improved progression-free survival (PFS) and overall survival (OS) versus Rd in tran...

Antichains for Concurrent Parameterized Games

Concurrent parameterized games involve a fixed yet arbitrary number of players. They are described by finite arenas in which the edges are labeled with languages that describe the possible move combinations leading from one vertex to another (n players yield a word of length n)....

Dual Porphyrin Sensitized Photocatalytic System for Visible‐Light‐Driven CO 2 Reduction

Dye‐sensitized photocatalysis offers a powerful strategy for combining the molecular selectivity of transition‐metal catalysts with the robustness and charge‐separation capabilities of semiconductor materials. Herein, we report a dual porphyrin–sensitized TiO 2 platform for visib...

Determinants of failure of midazolam monotherapy during continuous deep sedation until death: evidence from a French cohort in a palliative care unit

Abstract Background Continuous deep sedation until death (CDSUD) is a legally regulated practice in France relying primarily on midazolam as first-line therapy. However, additional sedative agents are frequently required, and determinants of failure of midazolam monotherapy remai...

Former les enseignants spécialisés au numérique : effets à court terme d'une activité d'appropriation instrumentale

International audience

A multiday outdoor festival combining breathwork and cold water immersion is associated with reduced trait anxiety in a naturalistic pre-post study

Abstract Breathwork and cold exposure attract growing public interest, yet little is known about their psychological effects in real-world multi-day formats, and most evidence concerns acute physiological or state-level outcomes rather than more dispositional markers. This natura...

The plasma-wall dynamic: Well-posedness

We prove existence and uniqueness in BV for a Vlasov-Poisson boundary value problem which takes into account a nonlinear boundary condition at the boundary on the electric potential. It models the dynamical interaction between a plasma and an electrically isolated metallic wall....

Serum GFAP and Age Accurately Distinguish AQP4 ‐ IgG Positive and Double Seronegative NMOSD From MOGAD After a Recent Attack

BACKGROUND: Serum neurofilament-light chain (sNfL) and glial fibrillary acidic protein (sGFAP) are associated with multiple sclerosis (MS) activity. This study aimed to identify patient- and disease-level determinants of sNfL and sGFAP and to evaluate their ability to support dif...

ALE-based finite element modeling of needle-punching using embedded 1D yarns in a 3D preform

Needle-punching is widely used to introduce through-thickness reinforcement into fibrous preforms for composite materials. During the process, barbed needles repeatedly penetrate stacked layers and transfer fibers from the in-plane directions toward the thickness direction, progr...

Measuring children’s HRQoL via self-reports and parent proxy-reports in the French Enabee 2022 study: an evaluation of the psychometric properties of both versions of the French KINDL-R questionnaire

Child well-being policies require quality data that takes children’s perspectives into account, recorded through appropriate, accurate and reliable measurement instruments. This study evaluated the psychometric properties of two versions of the KINDL-R questionnaire used in the 2...

Measurements of the production of W$$^{\pm }$$ and Z$$^0$$ bosons in pp collisions at $$\sqrt{s} = 13$$ TeV

Abstract Measurements of the production of the W $$^{\pm }$$ ± and Z $$^0$$ 0 bosons at midrapidity in pp collisions at $$\sqrt{s} = 13$$ s = 13 TeV with ALICE at the Large Hadron Collider (LHC) are presented. The W $$^{\pm }$$ ± and Z $$^0$$ 0 bosons are detected via their (di)e...

An inertial‐based spiral device for separating rare tumor cells from liquid biopsies

Abstract Early detection of primary tumors and metastatic processes increases the success of anti‐tumor therapies and favors good prognoses. Within the current range of methods available to detect the presence of tumors, liquid biopsy is receiving particular attention as it is a...

A framework for outcome determination of nosocomial pneumonia treatment in ventilated critically ill patients

Abstract Background Treatment failure of hospital-acquired (HAP) and ventilator-associated pneumonia (VAP) is a common endpoint in clinical research, yet the absence of a reproducible definition hampers comparability across studies. We propose an operational framework for assessi...

Lenalidomide maintenance after initial immunochemotherapy in chronic lymphocytic leukaemia—Final analysis of the international phase III CLL6 RESIDUUM study of the ALLG and FILO groups

Summary Most patients treated for chronic lymphocytic leukaemia (CLL) fail to achieve measurable residual disease (MRD) negativity. The role of maintenance with the immunomodulatory drug lenalidomide in these patients is unclear. A randomised multicentre phase III trial (ACTRN126...

Ligand‐Dependent Locally Excited and Charge‐Transfer Emission in Linear Copper(I) Mesoionic Carbene Luminophores

ABSTRACT We describe the synthesis of a family of photoemissive linear Cu(I) complexes bearing mesoionic carbenes (MIC) and amido ligands of the general formula Cu(MIC)NR 2 (NR 2 = carbazolide, diphenylamide). Careful tuning of the electronic and structural properties of both lig...

Beta Atlas: Charting Global Production of Nonconventional β − -Emitters for Targeted Radiopharmaceutical Therapy—Part 1

β-minus particle (β−)–emitting radionuclides have long been central to targeted radiopharmaceutical therapy. Interest in expanding their repertoire beyond conventional options has grown over time, as the need for radionuclides with different emission profiles and theranostic pote...

Integration of dentists into primary care teams in underserved areas: a qualitative study

Abstract Background Integrating oral health into primary care is increasingly promoted to enhance coordinated, patient-centred care, particularly in underserved areas experiencing workforce shortages. In France, multiprofessional primary care teams organised under the Société Int...