MRC University of Glasgow Centre for Virus Research

Global spread and evolutionary trajectories of HIV-1 CRF01_AE: Insights from phylogenetic analysis

HIV-1 circulating recombinant form (CRF) 01_AE has driven major HIV epidemics across Southeast and East Asia for decades, yet the mechanisms underlying its long-term regional spread remain poorly resolved. Using near-complete genome sequences and Bayesian phylogeographic reconstr...

Reverse genetics and comparative pathogenesis of Lone Star virus

ABSTRACT Lone Star virus (LSV) is a bandavirus first isolated from Amblyomma americanum ticks in the United States and is phylogenetically related to severe fever with thrombocytopenia syndrome virus (SFTSV), Heartland virus (HRTV), and Bhanja virus, each of which has been associ...

Quantification of absolute IgG concentration in bat sera

Abstract Bats are endowed with a remarkable capacity to withstand important pathogens through evolutionary adaptations in their immune systems. Antibodies are essential component of the adaptive immune response and serve as a crucial biomarker, indicating both present and past pa...

Colonisation and temperature-driven variation in life-history traits of the West Nile virus vector Culex pipiens at its Northern European limit

Abstract Background Mosquito-borne diseases (MBDs) are increasing worldwide driven by factors such as travel, land-use change, global trade, and climate warming. In Europe, Culex pipiens sensu lato (s.l.)—the primary vector of West Nile and Usutu viruses—is widespread and an incr...