Ministry of Education of the People's Republic of China

stDSVA: spatial transcriptomics deconvolution with a semi-supervised framework and cell type variation analysis

Spatial transcriptomics (ST) integrates transcriptomic profiling with tissue architecture, enabling the investigation of spatial heterogeneity in gene expression within intact tissues. However, due to the limited resolution of many current ST platforms, computational deconvolutio...

A numerical investigation on ultimate strength of marine sandwich composites under combined biaxial compression and lateral pressure

With the development of large-scale and light-weight ships, sandwich composites are increasingly used in hull structures because of their advantages of light weight, excellent mechanical properties, and corrosion resistance. Due to the synergistic effect among materials, sandwich...

Rock Pillar Fracture-Induced Vibration Characteristics and Rock Burst Mechanism in Steeply Inclined Extra-Thick Coal Seam Group Mining

Clarifying the dynamic mechanism of rock pillar fracture and its rock burst-inducing mechanism is fundamental for the prevention and control of rock burst disasters in steeply inclined extra-thick coal seam groups. In this study, field monitoring, theoretical analysis, and numeri...

In vivo labeling–based proteomic analysis of early follicle oocytes and cisplatin-induced alterations in mice

Abstract A systematic proteomic profile of oocytes from early-stage follicles, particularly primordial follicles, is critical to protect female reproductive capacity in the context of chemotherapy, yet progress has been hindered by the rarity of oocyte samples and technical chall...

Classification of unsound maize kernels using hyperspectral imaging and a dual-domain Mamba network

Accurate identification of unsound maize kernels is critical for reliable grain quality evaluation and safety management during storage. However, spectral variability among kernel components and complex morphological traits present significant challenges for conventional inspecti...

Reliability and diagnostic performance of radiologic indices of the proximal humerus in evaluating bone mineral density: a retrospective study

Proximal humerus fractures (PHFs) are the third most common osteoporotic fractures. Assessment of bone mineral density (BMD) is clinically relevant in patients with PHFs. Several studies have proposed the use of radiologic indices, including the average cortical bone thickness (C...

Small vulnerable newborns and prenatal exposure to organophosphate esters: Insights from the Ma'anshan Birth Cohort

Evidence on the association between prenatal exposure to organophosphate ester (OPE) and small vulnerable newborn components is limited and inconsistent. This study included 3208 mother-child dyads from the Ma'anshan Birth Cohort. In the first, second, and third trimesters, urine...

Integrated metagenomic and phosphorus fractionation analyses elucidate the mechanism driving soil phosphorus immobilization under erythromycin stress

Erythromycin (EM) is widely detected in agroecosystems, yet its mechanistic impact on microbially driven soil phosphorus (P) cycling remains limited. Here, we integrated Hedley P fractionation with metagenomic sequencing in soil microcosms exposed to EM (0, 10, and 50 mg/kg) to t...

Effects of groundwater level decline on shallow soil water in grassland open-pit mining areas: Water vapor migration and water sources estimation

Study region The Chenqi Coalfield in the Hulunbuir grassland, a typical semi-arid grassland open-pit mining area in Inner Mongolia, China, where mining has caused severe groundwater level decline. Study focus This study adopted in situ monitoring and hydrogen-oxygen stable isotop...

Advancing Energy Efficiency in Smart Windows via Dual‐Responsive Electro‐Thermochromism

ABSTRACT Implementing dynamic smart windows is imperative toward the construction of net‐zero buildings. However, the prevailing ion (de‐)embedding‐based electrochromic (EC) or thermosensitive hydrogel‐based thermochromic (TC) windows fail to achieve large optical modulation acro...

Hybrid intelligent strategy driving high-dimensional encrypted orbital angular momentum comb multicasting towards optical data-transmission networks

Abstract Achieving higher degrees and dimensions of light is one of the accessible paths for increasing the capacity of optical data-transmission systems. Orbital angular momentum (OAM), owing to its infinite and mutually orthogonal nature, offers a promising carrier for high-cap...

Local genetic distance-guided qPCR method for genotyping canine/feline coronaviruses

Canine coronavirus (CCoV) and feline coronavirus (FCoV) are highly infectious in companion animals. Nevertheless, due to genomic recombination and mutagenesis of the two CoVs, these difficulties dampen their precise diagnosis especially by genotypes. Herein, we addressed these pr...

RL-Augmented Dual Robust Adaptive Propagated Interval Observer for Actuator and Residual-Framed Sensor Fault Detection and Isolation in Underactuated AUVs

Reliable fault detection and isolation (FDI) for actuators and sensors in underactuated autonomous underwater vehicles (AUVs) is challenging because nonlinear hydrodynamic coupling redistributes fault signatures, and persistent ocean currents can trigger false alarms. This paper...

A game-theoretic attack-defense framework for the study of network resilience

The rapid evolution of communication technologies and the Internet of Things has enhanced system interconnectivity, allowing localized disruptions to cascade into failures. Many such breakdowns are not purely accidental but emerge from intentional countermeasures that influence o...