Menoufia University

Unmasking the Hidden Cancer Risk in Chronic Rhinosinusitis: Systematic Review and Meta-Analysis

Chronic rhinosinusitis (CRS) has a complicated, multifaceted etiology. It is distinguished by inflammation of the nasal and sinus mucosa. We aim to investigate the association between CRS and various malignancies, as well as their underlying mechanisms. We included published stud...

Early Hemodynamic Prediction: A Critical Review and Clinical Insights

Blood flow abnormalities are central to cardiovascular and cerebrovascular diseases, yet early detection remains challenging due to invasive or resource‑intensive traditional methods. Deep neural networks (DNNs) offer a potential non‑invasive alternative by inferring hemodynamic...

Mesenchymal stem cells modulate pancreatic and splenic inflammation through PI3K/AKT/mTOR and TGF-β signalling in diabetic rats

Bone marrow-derived mesenchymal stem cells (MSC) can attenuate diabetic organ damage through immunomodulatory and paracrine mechanisms, yet the specific signalling pathways engaged in the pancreas and spleen remain poorly characterized. This study investigated the effects of a si...

Rabies and rabies prophylaxis in Egypt: a nationwide cross-sectional study that calls for action

BACKGROUND: Rabies is a fatal but preventable viral disease that poses a global health threat, especially in developing countries. Despite the high incidence of animal bites reported annually in Egypt, limited data exist regarding the knowledge, attitudes, and practices (KAP) of...

DA-MC-SEP: a distance-aware multi-hop clustering and stable election protocol for heterogeneous WSNs

Abstract Wireless Sensor Networks (WSNs) consist of large numbers of sensor nodes (SNs) operating under strict energy constraints, making efficient routing protocols essential for extending network lifetime and ensuring reliable data delivery. This paper introduces a Distance-Awa...

The impact of health education intervention on knowledge, attitude, and practice of office workers about office ergonomics: a randomized controlled trial

Abstract Background Ergonomics is fundamental to improving safety and efficiency in offices. Therefore, the purpose of this study was to assess the effect of a health education intervention on office workers’ knowledge, attitude, and practice (KAP) regarding ergonomics and to det...

Ovarian Cyst Fluid as a Resource for Diagnostic and Prognostic Biomarker Discovery in Ovarian Lesions

Background/Objectives: Differentiating benign, borderline, and malignant ovarian cystic lesions before surgery remains challenging, and many women undergo operations for lesions that prove benign. Most cystic lesions contain fluid that lies in direct contact with the lesion and f...

Conserving and managing mosaics by reburial: safeguarding the ‘Baths of Regio VII’ at Sabratha, Libya

Abstract This article presents a mosaic reburial in the Baths of Regio VII at Sabratha (Libya) which took place in April 2025 after a long gestation. It documents the practical, material and logistical dimensions of safeguarding vulnerable pavements in situ which have been long e...

Profiles of self-reported emotional intelligence and cognitive emotion regulation strategies among university students: a latent profile analysis

Self-reported emotional intelligence (EI) is associated with psychological adjustment, but most studies of its links with emotion regulation (ER) are variable-centred. Students could differ in the configuration of EI dimensions (e.g., high emotion appraisal with low perceived reg...

Evaluating Aspergillus brasiliensis (ATCC 16404) for the bioaccumulation and solubilization of selenium nanoparticles

Abstract The extensive application of selenium nanoparticles (Se-NPs) in research and industry for their antibacterial, antioxidant, and anticancer properties raises concerns about environmental contamination and ecological risks. This highlights the need for eco-friendly methods...

Magnetically recoverable carboxymethyl chitosan/cerium dioxide/iron oxide tricomponent nanocomposite: A biobased photocatalyst for environmental remediation and antimicrobial applications

Carboxymethyl chitosan (CMCs) is extensively used for wastewater treatment owing to its active functional groups. For improved efficiency, a nanocomposite of two metal oxides, cerium dioxide (CeO 2 ) and iron oxide (Fe 2 O 3 ), was prepared by ball milling. Two loadings (0.15 and...

Assessment of serum vitamin D level in relation to liver functions and fibrosis in cholestatic infants with biliary atresia

Abstract Background Biliary atresia (BA) is the most urgent cause of neonatal cholestasis and is frequently complicated by fat-soluble vitamin deficiency. This study aimed to investigate serum vitamin D status in cholestatic infants with BA and its relationship to liver function...

Assessment of IL-27 T4730C polymorphism and its serum levels in neonatal cholestasis patients

Abstract Background The immune system and many genes have been linked to bile tract damage in neonatal cholestasis (NC), resulting in liver retention of biliary contents. The most commonly recognized cause of NC is biliary atresia (BA). Objectives The study investigated the effec...

Melatonin Supplementation in the Management of Irritable Bowel Syndrome: An Updated Systematic Review and Meta‐Analysis

ABSTRACT Background Irritable bowel syndrome (IBS) is a common disorder of gut–brain interaction characterized by recurrent abdominal pain and altered bowel habits, with substantial effects on quality of life and healthcare utilization. Melatonin has been proposed as a potential...

Heat transfer and fluid dynamic performances of a stepped solar still: CFD simulation and experimental validation

Abstract In this work, a novel transient CFD modeling procedure for a stepped basin solar still (SBSS) was developed, with no requirement to specify the glass cover and basin water temperatures as boundary conditions. The solar irradiation absorption and heat transfer by radiatio...

Predictors of no-reflow phenomenon in patients with type 2 diabetes mellitus undergoing elective percutaneous coronary intervention: the emerging role of the triglyceride–glucose index

Abstract Objective To determine the prevalence and predictors of the no-reflow phenomenon in patients with type 2 diabetes mellitus (T2DM) undergoing elective percutaneous coronary intervention and to evaluate the predictive value of the triglyceride–glucose (TyG) index. Methods...

Molluscicidal activity, effects on mucus secretion, and joint actions of Brassica rapa and Salvia officinalis extracts with metaldehyde against Monacha obstructa

Abstract Turnip seed ( Brassica rapa ) and sage leaf ( Salvia officinalis ) extracts were prepared by macerating plant materials in 80% methanol at a ratio of 1:10 (w/v) for five days. The molluscicidal activity of the tested plant extracts and metaldehyde was evaluated against M...

Efficacy and safety of oncolytic herpes simplex virus therapy in solid tumors: a systematic review and meta-analysis of 38 clinical trials

Abstract Background Oncolytic herpes simplex virus (oHSV) therapy represents a novel immunotherapeutic approach for solid tumors. Despite regulatory approval of talimogene laherparepvec (T-VEC) for advanced melanoma, comprehensive pooled estimates of efficacy and safety across di...

Knowledge, attitudes, and practices (KAP) toward stroke prevention among hypertensive patients in Egypt: a multicenter cross-sectional study

Abstract Stroke is the second most common cause of death worldwide and represents a major health concern in Egypt. Hypertension is the most important modifiable risk factor for stroke; we aim to assess knowledge, attitudes, and practices (KAP) toward stroke prevention among hyper...

Effectiveness of a Mobile Application with an AI-Powered Chatbot to Enhance Nursing Students' Awareness of Substance Abuse Prevention: An Interventional Study

Background Substance abuse among university students has emerged as a significant problem from a public health perspective, with specific patterns observed among the population in Jordan. Chatbots developed using artificial intelligence are effective instruments in health educati...