Marwadi University

Myricetin Modulates Quorum Sensing-Associated Phenotypes, Virulence, and Biofilm Formation in Pathogenic Bacteria: In Vitro and In Silico Studies

Background/Objectives: The rapid emergence of antimicrobial resistance (AMR) among pathogenic bacteria has necessitated the development of alternative therapeutic strategies that target bacterial virulence rather than cell viability. Methods: In this study, the flavonoid myriceti...

An interpretable feature-augmented stacked ensemble framework for student dropout prediction

Abstract Student dropout prediction is regarded as one of the significant research fields in educational data mining. It aids the sustainability of institutions and early interventions in schools. This study proposes an Enhanced Stacked Dropout Predictor (eSDP), which is a featur...

Design and Synthesis of Purine–Biphenyl Hybrids: Cytotoxicity, ADMET Analysis and MD Simulation Study

A novel series of purine–biphenyl hybrids was designed and synthesized by linking 2,6-dichloropurine with methyl-2-cyanobiphenyl, aiming to develop cytotoxic agents targeting the Epidermal Growth Factor Receptor (EGFR). Structural diversity was introduced via C6 substitution with...

Seismic fragility and reliability of elevated water tanks as urban water-supply lifeline components under near-fault ground motions: a demand amplification framework

Abstract Urban water-supply systems depend on elevated water tanks for storage, pressure support, firefighting, and post-earthquake service continuity. This study evaluates the component-level seismic fragility and reliability of three 250 m 3 Intze-type reinforced-concrete frame...

Landslide Susceptibility Mapping in the Garhwal Himalaya Integrating Seismic Shaking and Active‐Fire Predictors With an XGBoost Model

ABSTRACT The Garhwal Himalaya of Uttarakhand, India, is a tectonically active, deeply dissected orogen in which landsliding is conditioned by a heterogeneous mix of topographic, geological, hydro‐climatic, seismic and anthropogenic controls. Reliable, high‐resolution susceptibili...

Advanced design of highly efficient graphene-based Ti-GaSb-Si based solar absorber for mining related applications optimized using machine learning

The solar absorber is a necessity in renewable energy applications; it has been widely used and investigated in various materials and layer configurations. Analysis of the design and materials, with height as a parameter, can be developed for effective solar absorber design as a...

Improving pharmacokinetics and pharmacodynamics of berberine hydrochloride using solid dispersion: A therapeutic approach to hyperlipidemia

Berberine is an isoquinoline alkaloid that acts as a natural PCSK9 inhibitor. By inhibiting PCSK9, it upregulates Low-Density Lipoprotein (LDL) receptors and helps maintain lipid metabolism. Although it is a promising hypolipidemic agent, its clinical application is limited by po...

Collective variable approach to soliton dynamics in the Kuramoto–Sivashinsky equation for nonlinear transport and pattern formation

In the present article, the collective variable (CV) approach is implemented to investigate soliton dynamics associated with the Kuramoto–Sivashinsky equation, a nonlinear fourth-order partial differential equation frequently arising in nonlinear transport phenomena, dissipative...

The rise of oral vaccines in modern healthcare- An emergence of paradigm shifting

The administration of vaccines stands as one of the most impactful prophylactic measures against infectious diseases for safeguarding global serenity. Although oral administration of vaccines is the most preferred route over parenteral administration, it represents a gold standar...

Experimental and thermal performance evaluation of a PCM-enhanced solar water heater with a spiral coil heat exchanger

Latent heat thermal energy storage is an effective approach for enhancing the performance of solar water heating (SWH) systems by storing surplus thermal energy and delivering it during periods of low solar availability. In this study, the thermal performance of a solar water hea...