Institution
Marine Biomedical Research Institute of Qingdao
Recent research
Abstract The NLRP3 inflammasome plays a critical role in the pathogenesis of inflammatory diseases and has emerged as a promising therapeutic target. Our preliminary studies revealed that istradefylline, an anti-Parkinsonian agent, exhibits moderate NLRP3 inhibitory activity. Fur...
- BiologyOpen access
Recent Advances in the Antihyperlipidemic Activity of Marine Polysaccharides
Hyperlipidemia is a chronic metabolic disorder in humans, contributing to the onset of cardiovascular diseases (CVDs) that remain the leading cause of death worldwide. Current clinical antihyperlipidemic agents are often accompanied by diverse adverse side effects. Therefore, dev...
- Climate & Environment
ABSTRACT Based on the introduced founder sporophytes, a set of S. japonica varieties and a few hybrid kelp have been bred and intensively cultivated in China. The cultivation of S. japonica has been running up against the impasse of germplasm degeneration characterized by low gro...
- BiologyOpen access
Abstract Postmenopausal osteoporosis is characterized by a disruptive bone‑fat imbalance, yet effective therapies remain limited. Here, for the first time, we link the traditional use of fish maw heat‑treated with clam shell powder (CPFM) to the restoration of bone‑fat balance. U...
- Health & MedicineOpen access
Nephrectomy is standard for kidney tumors and living kidney donation, but postoperative chronic kidney disease (CKD) is a critical determinant of long-term outcomes. Risk factors for incident CKD after unilateral nephrectomy remain incompletely synthesized. PubMed, Embase, Web of...
- Health & MedicineOpen access
OBJECTIVES: Postpartum depression (PPD) profoundly affects maternal health and disrupts mother-infant bonding, with lasting effects on infant development. The causal roles of hormones that change most dramatically during the perinatal period, including estradiol, cortisol, and pr...