Mansoura National University

Cloud-assisted IoRT framework for latency-aware analytical kinematic control of a six-DOF robotic manipulator

Abstract The Internet of Robotic Things (IoRT) has introduced new possibilities for distributed and scalable robotic control by combining industrial manipulators with cloud-based computation and networked communication infrastructures. However, the deployment of cloud-assisted ro...

Pyrazolo[3,4-b]pyridine: a privileged scaffold for the synthesis of anti-Alzheimer’s agents

Abstract Alzheimer’s disease (AD) is known to be the most prevalent neurodegenerative disorder that results in dementia and causes a variety of cognitive symptoms. There are many important aspects of AD that should be considered, even though the exact sequence of events is unclea...

Fasudil Protects Against Diclofenac-Induced Hepatorenal and Gastric Injury via Modulation of ROCK/TLR4/SIRT1 Signaling and Preservation of Tight Junctions

Background: Diclofenac is a widely consumed non-steroidal anti-inflammatory drug, yet its clinical utility is limited by severe hepatotoxicity, acute kidney injury, and gastric ulceration. While the RhoA/ROCK pathway is implicated in inflammation, its potential as a therapeutic t...