Makerere University

“Gender-based violence is the last thing they will think about”: a qualitative study on multilevel factors affecting gender-based violence screening and response in HIV care, Uganda, 2023

Uganda’s Ministry of Health (MOH) adopted the World Health Organization’s guidelines to incorporate routine gender-based violence (GBV) screening, counseling, and referrals in health care settings, including HIV care; however, considerable implementation barriers exist. This stud...

Flooding-driven sanitation failure and enteric disease risk in urban informal settlements: Cholera as an illustrative case for climate-resilient sanitation in low- and middle-income countries

Climate change is intensifying rainfall extremes and urban flooding, amplifying public health risks in settings with fragile sanitation and drainage systems. In dense urban informal settlements, floods can overwhelm onsite sanitation and fecal sludge management systems, causing p...

Enhancing the utility of exploratory ‘factors associated with’ studies in global mental health: the importance of context in Sub-Saharan Africa

Abstract “Factors associated with” studies, exploratory multivariable regression analyses that do not begin with a prespecified primary exposure, have recently come under increasing criticism, with some arguing that they are methodologically weak and contribute little to scientif...

Early insights into predicted efficacy of Ebola monoclonal antibodies for the 2026 Bundibugyo virus disease outbreak

The 2026 Bundibugyo virus disease (BVD) outbreak in the DRC and Uganda raises urgent questions about the efficacy of existing Ebola virus (EBOV) monoclonal antibodies (mAbs) against Bundibugyo virus (BDBV). Here, we perform genomic and structural analyses of 44 BDBV sequences, in...

Strengthening systems to monitor antibiotics. An action oriented approach

Background Antibiotics have become lynchpins of our modern systems of healthcare, animal health and agriculture. Monitoring the types and volumes of antibiotics distributed, used and discharged across these systems is critical to provide evidence for action. With limited resource...

Metrics of misrecognition

Purpose This conceptual paper aims to provide a critical analysis of the practice arrangement bundles governing promotion and evaluation systems within flagship universities as a socioeconomic system profoundly shaping academic identity and institutional ethics. Design/methodolog...

Critical antecedents for successful labor-management partnerships (LMP): taxonomy, levels and the “black boxes”

Purpose Employment relations studies have examined the notion and practice of labor-management partnership (LMP); yet, a delineation of overarching explanations for successful LMP remain outstanding. This study sought to identify and classify critical antecedents for successful L...

Entrepreneurial bricolage in practice: an exploratory qualitative Inquiry among Ugandan microentrepreneurs

This paper explores how microentrepreneurs interpret and enact entrepreneurial bricolage in Uganda’s resource-constrained environment. An exploratory qualitative design was employed, using semi-structured interviews with 40 microentrepreneurs in Kampala District. Data were themat...

Validity of the center for epidemiological studies depression (CES-D) scale for depression screening in postpartum adolescents in Uganda

In Uganda, 25% of pregnancies occur among teenagers and an estimated 20.7% have postpartum depression. Postpartum depression is often underdiagnosed due to insufficient mental health resources and few validated screening tools for adolescent mothers. Addressing this gap, psychome...

Lead-time management and supply chain performance in Ugandan public health institutions

Purpose This study examines the association between lead-time management and supply chain performance in Ugandan public health institutions by investigating whether the order-to-delivery cycle and the cash-to-cash cycle are associated with supply chain flexibility, reliability an...

Actualizing the implementation of the underutilized low-cost, life-saving intervention of skin-to-skin contact immediately after birth in a regional referral hospital in Uganda

As a low-resource opportunity to decrease neonatal mortality, skin-to-skin contact during the first hour after birth is an evidence-based best practice which is implemented inconsistently world-wide. As described in the 2023 international research and practice guideline, skin-to-...

Neurocognitive performance and activities of daily living in older people with HIV: a cross-sectional study in Uganda

Neurocognitive impairment is prevalent among older people living with HIV (OPLWH) ≥ 60 years despite effective antiretroviral therapy (ART). We aimed to investigate low cognitive performance and its association with functional status among OPLWH ≥ 60 years in Uganda. We conducted...

Uptake of R21/Matrix-M malaria vaccine and associated factors among children eligible for vaccination in Kole and Kwania districts, Northern Uganda: a cross-sectional study

The introduction of R21/Matrix-M (R21) vaccine as a malaria control strategy provides an opportunity to reduce the disease burden. However, there is limited evidence on its uptake and what affects the uptake, information that is important for the successful implementation of the...

Carbon finance as climate adaptation depends on smallholder livelihood contexts in Uganda

Nature-based solutions in voluntary carbon markets have become increasingly important instruments for financing climate adaptation and mitigation, yet limited evidence exists on whether and how these mechanisms enable smallholder adaptation. This research examines smallholder par...

The impact of financial inclusion on economic growth in Uganda from 1986 to 2022

This study evaluates the impact of financial inclusion on economic growth in Uganda, using 37 years of annual data (1986–2022) obtained from the World Development Indicators database. We estimate financial inclusion (in terms of domestic credit to the private sector) as a percent...

Schiff Base Derivatives of Benzothiazole and Benzamide as Promising Antimicrobial Agents: Integrated In Silico and In Vitro Evaluation

Antimicrobial resistance (AMR) remains a critical global health challenge, demanding new scaffolds with potent and broad‐spectrum activity. In this work, a library of Schiff‐base derivatives of benzothiazoles ( 2a–2f ) and benzamides ( 5a–5i ) was designed, synthesised via a micr...

Examining Data-Driven Approaches for Clean Air Advocacy in a Changing Climate: a Scoping Review

Abstract Purpose of Review Air pollution remains a global public health and climate challenge, causing millions of premature deaths annually and disproportionately affecting marginalised communities. This scoping review examines how data-driven approaches have been used to advoca...

HIV and anticholinergic burden: Towards a pragmatic stewardship algorithm

Abstract Background Multimorbidity and polypharmacy increase exposure to medications with anticholinergic properties in people with HIV. In elderly people, higher anticholinergic burden (ACB) is linked to cognitive impairment, falls, functional decline and mortality, whose risk i...

Analytical performance verification of the Deeplex Myc-TB assay using well-characterized Mycobacterium tuberculosis proficiency testing isolates

Rapid and accurate detection of drug-resistant Mycobacterium tuberculosis is critical for effective patient management and tuberculosis (TB) control. Targeted next-generation sequencing (tNGS) assays such as Deeplex® Myc-TB offer rapid detection of resistance-associated mutations...

Fear, stigma and Uncertainty: The short and long-term effects of Ebola on survivors, affected families, and community in Bundibugyo, Western Uganda

Abstract In 2014, Uganda was identified as a high-risk country for Ebola Virus Disease (EVD), with a series of outbreaks recorded since 2000. In 2007, the second outbreak in Bundibugyo district resulted in 149 reported cases and 37 confirmed Ebola deaths. Through the outbreak res...