Mahindra Group (India)

Discovery and Modulation of an Unusual Terminal Mismatch Bypass Activity Involving 3′-Phosphorothioated Primers and Commercial Strand Displacement DNA Polymerases

Abstract Phosphorothioated (PST) oligonucleotides are extensively used in RNA therapeutics and biosensing applications. PST-modified linkages remain part of 13 approved oligonucleotide drug backbones (out of 23 total approved drugs). Despite the widespread utilization of PST link...

Efficient One Pot Synthesis of 3-Methyl-4-(Hetero) Arylmethylene Isoxazole-5(4H)-Ones Derivatives Catalyzed by [EMIm][BH3CN] Ionic Liquid Under Reflux and Microwave Conditions

AbstractHere, we have developed an expeditious and efficient protocol for the synthesis of isoxazol-5(4H)-onederivatives catalysed by the ionic liquid [EMIm][BH3CN] using ethanol as a solvent under microwaveirradiation (MW, 240 W, 4–6 min) and conventional reflux conditions. The...

Gen Z vs Sanatan Dharma: Religious, Traditional and Cultural Practices – A Study on the Perception and Continuity of Sanatan Values in the Modern Scientific Age

Abstract Generation Z represents a generation influenced by digital technology, globalization, scientific advancement and changing social values. This study examines the perception, awareness and acceptance of Gen Z towards Sanatan Dharma's religious, traditional and cultural pra...

Gen Z vs Sanatan Dharma: Religious, Traditional and Cultural Practices – A Study on the Perception and Continuity of Sanatan Values in the Modern Scientific Age

Generation Z represents a generation influenced by digital technology, globalization, scientific advancement and changing social values. This study examines the perception, awareness and acceptance of Gen Z towards Sanatan Dharma's religious, traditional and cultural practices. S...

Reaction–Transport Coupling Drives Spatiotemporal Organization in Fuel‐Driven Supramolecular Polymerization

ABSTRACT Chemically fueled supramolecular systems provide a versatile platform for generating nonequilibrium structures and dynamical instabilities, including chemical oscillations and traveling waves reminiscent of biological organization. However, a minimal mechanistic framewor...

Unlocking the potential of agro-industrial wastes as valorizable substrates for bacterial carotenoid production – A comprehensive review

The sustainable production of valorizable bacterial metabolites, such as carotenoids, using inexpensive substrates or waste materials, including agrowaste, faces several challenges. Research in this area needs to gain momentum to achieve green goals for a better tomorrow. Efficie...