Loma Linda University

“I’m never enough”: Associations of childhood emotional abuse subtypes with overweight preoccupation and dietary restraint among women

Childhood emotional abuse from authority figures encompasses verbal abuse, emotional rejection, and overexpectations. Although global emotional abuse is an established correlate of body dissatisfaction and disordered eating, the unique roles of these specific subtypes remain unde...

Exploring the Likelihood of Healthcare Students to Advise Patients on the Health Benefits of Predominantly Plant-Based Diets

The aim of this study was to survey select healthcare students in the Americas about their likelihood to advise on health benefits of predominantly plant-based diets to noncommunicable disease patients; and to identify possible demographic, academic, and psychographic association...

Sickle Cell Disease-Related Dating Challenges, Intimacy, and Family Planning Decisions

Individuals living with sickle cell disease (SCD) experience reproductive health challenges related to unpredictable pain crises and hospitalizations. However, little research has examined how SCD-related pain influences dating and reproductive decisions. This qualitative phenome...

The MoCA Memory Index Score (MIS) as an indicator of episodic memory impairment and its implications for cognitive screening in a mixed clinical sample

OBJECTIVE: The Montreal Cognitive Assessment (MoCA) Memory Index Score (MIS) has shown promise as a brief indicator of episodic memory decline, but its correspondence with standardized neuropsychological memory measures in diagnostically heterogeneous clinical populations remains...

Deep learning quantification of mouse nesting behavior for tracking cognitive decline in models of aging & Alzheimer’s disease

Abstract The aging brain and development of Alzheimer’s disease (AD) are characterized by neurological degeneration. Nest-building performance captures deteriorating cognitive and motor functions in rodent models of AD; albeit qualitative while limited in physiological scope. To...

Early Intraretinal Fluid Reduction is Linked to Vision Gains in Patients with Diabetic Macular Edema

This analysis evaluated the impact of early intraretinal fluid (IRF) reduction on long-term visual outcomes in patients with diabetic macular edema (DME). This was a treatment-agnostic, post hoc analysis of pooled data from patients with DME in YOSEMITE/RHINE (NCT03622580/NCT0362...

Long‐term periodontal stability following palliative management of pemphigus vulgaris: A 5‐year case report

BACKGROUND: Pemphigus vulgaris (PV) is a chronic autoimmune mucocutaneous disorder that may cause painful oral erosions, mucosal fragility, and impaired oral hygiene, complicating periodontal treatment. This case report describes a staged, minimally traumatic approach to periodon...

Institutional Volume Explains Observed Facility-Level Differences in Survival Following Surgical Resection of Spinal Schwannomas: A National Cancer Database Study

Introduction Spinal schwannomas are benign tumors that comprise over 20% of primary intraspinal neoplasms. While gross total resection offers excellent local control, little is known about how facility-level factors correlate with survival. This study evaluated patient and instit...

High-grade astrocytoma with piloid features: a clinical and genomic analysis of prognostic factors using a large cohort

BACKGROUND: High-grade astrocytoma with piloid features (HGAP) is a recently defined tumor type that is not well-understood. Prognostic factors of clinical outcomes are not well-established. METHODS: Methylation profiling was performed on tumor samples, many at the National Cance...

Cutting to the Truth: Are We Measuring Osteotomy Parameters Correctly?

Purpose Traditional lower limb deformity analysis in pediatrics and adults centers on the anatomical center of the knee. However, in high tibial osteotomy (HTO) for medial compartment knee osteoarthritis (KOA), the surgical goal is often valgus overcorrection toward a lateral wei...

Feasibility of integrating the VIA survey into medical education: a strengths workshop and longitudinal mentoring curriculum

Medical students experience high rates of stress and burnout, which negatively impact mental health and academic performance. Traditional resilience interventions often emphasize stress management and coping skills without explicitly focusing on the identification and use of pers...

Bioactive Microsurgery and CCL2

Peripheral nerve injuries often result in incomplete functional recovery, despite technically successful microsurgical repair. Traditional strategies focus on structural continuity but neglect the immunobiological environment critical for regeneration. CCL2 (monocyte chemoattract...

Superlarge-Bore Versus Large-Bore Aspiration Catheters in Mechanical Thrombectomy: A Multicenter Propensity-Matched Analysis

BACKGROUND AND OBJECTIVES: Aspiration catheters are an integral component of mechanical thrombectomy for acute ischemic stroke (AIS). Following early series demonstrating increasing procedural efficiency and improved outcomes with use of large-bore (LB) aspiration catheters, ther...

Multimethod examination of change in autistic preschoolers' emotion dysregulation in the context of parenting stress intervention

Background Many autistic preschoolers experience heightened emotion dysregulation and rely heavily on parents for co‐regulatory support, which may be compromised by elevated parenting stress. Methods We examined secondary outcomes of a randomized trial (ClinicalTrials.gov – NCT03...

Acute exposure to cell-free mitochondrial DNA induces pregnancy-specific aortic endothelial dysfunction and organ-selective inflammation in rats

Abstract Pregnancy complications such as preeclampsia are associated with circulating cell-free mitochondrial DNA (mtDNA), a damage-associated molecular pattern capable of activating Toll-like receptor 9 (TLR9). We hypothesized that acute mtDNA exposure induces maternal inflammat...

3D assessment of the marginal and internal gap and fracture load of ceramic surveyed inlays designed for removable partial denture support: An in vitro comparative study

PURPOSE: To assess the internal and marginal gaps and the fracture load of different machinable ceramics for an inlay acting as a support for a removable partial denture. MATERIALS AND METHODS: Sixty extracted human teeth (first maxillary premolar) were collected (n = 10 for each...

Role of the School Nurse in Providing School Health Services: Policy Statement

School nursing has evolved into an essential field bridging health care and education. School nurses play multifaceted roles, addressing direct care, care coordination, public health, leadership, and quality improvement. They manage communicable diseases, chronic conditions, ment...

Cross-sectional survey of perimenopausal women for menopause symptoms and attitudes in Singapore

OBJECTIVE: Menopause symptoms and experiences vary considerably between women and can be influenced by multiple biopsychosocial and cultural factors, age and ethnicity. This study investigated the symptoms and attitudes of perimenopausal women in Singapore. METHOD: Women aged 40-...

An epidemiological assessment of hemodialysis, continuous kidney replacement therapy, and peritoneal dialysis in pediatric acute kidney injury patients

INTRODUCTION: Hemodialysis (HD), peritoneal dialysis (PD), and continuous kidney replacement therapy (CKRT) are major modalities of kidney replacement therapy (KRT) in pediatric acute kidney injury (AKI). This study uses TriNetX data to identify clinical characteristics of pediat...

The janus-faced function of mesenchymal stem cells in oral cancer

Mesenchymal stem cells (MSCs), which exist in bone marrow, tooth pulp, and tumor microenvironments, have a dual role in oral malignancies. These cells interact closely with cancer stem cells (CSCs) and the tumor microenvironment (TME). On the one hand, MSCs accelerate the growth...