Loma Linda University

3D assessment of the marginal and internal gap and fracture load of ceramic surveyed inlays designed for removable partial denture support: An in vitro comparative study

PURPOSE: To assess the internal and marginal gaps and the fracture load of different machinable ceramics for an inlay acting as a support for a removable partial denture. MATERIALS AND METHODS: Sixty extracted human teeth (first maxillary premolar) were collected (n = 10 for each...

Acute exposure to cell-free mitochondrial DNA induces pregnancy-specific aortic endothelial dysfunction and organ-selective inflammation in rats

Abstract Pregnancy complications such as preeclampsia are associated with circulating cell-free mitochondrial DNA (mtDNA), a damage-associated molecular pattern capable of activating Toll-like receptor 9 (TLR9). We hypothesized that acute mtDNA exposure induces maternal inflammat...

Role of the School Nurse in Providing School Health Services: Policy Statement

School nursing has evolved into an essential field bridging health care and education. School nurses play multifaceted roles, addressing direct care, care coordination, public health, leadership, and quality improvement. They manage communicable diseases, chronic conditions, ment...

Cross-sectional survey of perimenopausal women for menopause symptoms and attitudes in Singapore

OBJECTIVE: Menopause symptoms and experiences vary considerably between women and can be influenced by multiple biopsychosocial and cultural factors, age and ethnicity. This study investigated the symptoms and attitudes of perimenopausal women in Singapore. METHOD: Women aged 40-...

The janus-faced function of mesenchymal stem cells in oral cancer

Mesenchymal stem cells (MSCs), which exist in bone marrow, tooth pulp, and tumor microenvironments, have a dual role in oral malignancies. These cells interact closely with cancer stem cells (CSCs) and the tumor microenvironment (TME). On the one hand, MSCs accelerate the growth...

An epidemiological assessment of hemodialysis, continuous kidney replacement therapy, and peritoneal dialysis in pediatric acute kidney injury patients

INTRODUCTION: Hemodialysis (HD), peritoneal dialysis (PD), and continuous kidney replacement therapy (CKRT) are major modalities of kidney replacement therapy (KRT) in pediatric acute kidney injury (AKI). This study uses TriNetX data to identify clinical characteristics of pediat...

Teclistamab Monotherapy in Relapsed or Refractory Multiple Myeloma: A Real-World Focused Systematic Review and Meta-Analysis of Efficacy and Safety

Background/Objectives: Teclistamab is a B-cell maturation antigen (BCMA)-directed bispecific antibody approved for relapsed or refractory multiple myeloma (RRMM). Although prior analyses have summarized teclistamab outcomes, some have included combination regimens or broader comp...