Institution
Korea Research Institute of Bioscience and Biotechnology
Recent research
- Health & MedicineOpen access
Chemotherapy for solid tumors has serious limitations due to acquired chemoresistance and frequent postsurgical recurrence. In this study, we developed a chemo-immunotherapy regimen combining a chemotherapeutic agent, a dendritic cell (DC)-activating cancer nanovaccine, and immun...
- Biology
Plasma Metabolomes Identify Distinct Asthma Metabotypes: Findings From the COREA Cohort
BACKGROUND: Phenotype-based asthma classification has limitations that have motivated endotype-based approaches grounded in pathophysiology. However, existing biomarkers offer limited specificity and clinical accessibility. Plasma metabolomics, which reflects disease-specific met...
- BiologyOpen access
Kidney organoids (KOs) are being actively developed and used as models for evaluating nephrotoxicity, which is an important process during drug development. To evaluate human pluripotent stem cell-derived KOs, various lineage markers have been used to confirm KO differentiation v...