KLE University

Salivary telomere length in oral leukoplakia and oral squamous cell carcinoma: A preliminary case- control study

Purpose To evaluate salivary telomere length as a potential non-invasive exploratory biomarker for early molecular alterations associated with oral leukoplakia and oral squamous cell carcinoma. Methods Forty-five participants were initially recruited: 15 healthy controls, 15 leuk...

Structure-based discovery of phospholipase A1 (PlaF) inhibitors in Pseudomonas aeruginosa using integrated in silico and experimental approaches

Phospholipase A1 (PlaF) is a membrane-bound virulence factor in Pseudomonas aeruginosa, involved in glycerophospholipid remodeling and host-pathogen signaling. Inhibiting PlaF represents a promising strategy to reduce the virulence and pathogenesis of multidrug-resistant P. aerug...

Early Survivorship Outcomes in Childhood Cancer Survivors: School Reintegration, Nutritional Status, and Revaccination

BACKGROUND: With improving survival in childhood cancer, the focus is shifting toward early survivorship, a critical period for recovery and transition to long-term care. Data from low- and middle-income countries (LMICs) on outcomes during this phase remain limited. METHODS: We...

A multi-technique analytical strategy for the standardization of Boswellia serrata : RP-HPLC quantification employing relative response factors, HPTLC fingerprinting, LC-MS/MS characterization

Boswellia serrata is a widely recognized medicinal plant whose therapeutic properties are primarily attributed to boswellic acids, making their reliable characterization and quantification essential for its quality assessment. This study established an integrated analytical strat...