Kitasato University

Non‐Covalent PL, CD, and CPL Activation of Linear Aromatic Oligomers within Axially Chiral Aromatic Capsules

ABSTRACT Covalent functionalization is requisite to enhancing/inducing the luminescent and chiroptical properties of oligo‐aromatic compounds, owing to their rigid framework and strong aggregation characters. Here we report that linear aromatic oligomers display intense PL, CD, a...

A Programmable Nanovesicle Platform for MegapascalPressure Sensing

Abstract Hydrostatic pressure (HP) is a subtle yet pervasive force that shapes chemistry and biology from the ocean floor to living cells─yet real-time HP sensing at the microscale remains elusive. Here, we report pyrene-modified polyionic complex vesicles (Pyr-PICsomes) as a cla...

De novo epilepsy after the occipital transtentorial approach: association with occipital lobe injury and persistent FLAIR lesions

The occipital transtentorial approach (OTA) is a useful surgical corridor for deep-seated lesions involving the pineal region, thalamus, ventral temporal structures, and posterior fossa. Although occipital lobe injury is a recognized complication of OTA, its relationship with pos...

Genomic resources of Ascidiella aspersa and comparative analysis across tunicates reveal class-level features and evolutionary diversification

Ascidiella aspersa is an invasive tunicate and one of the closest relatives of vertebrates. Despite its ecological nuisance, A. aspersa is anticipated to be a valuable model organism for developmental studies due to its remarkably transparent embryos. However, annotated genome as...

Balancing Circulatory Support and Ventricular Unloading in Post‐Infarction Ventricular Septal Perforation: A Computational Analysis of ECPELLA Support Configurations

BACKGROUND: Ventricular septal perforation (VSP) is a catastrophic complication of acute myocardial infarction frequently associated with cardiogenic shock. Combined venoarterial extracorporeal membrane oxygenation (VA-ECMO) and Impella support (ECPELLA) has emerged as a promisin...

A Melanoma Transplanted in Nude Mice Has Both Host‐ and Tumor‐Derived Blood Vessel‐ and Nerve‐Like Structures

Nestin-expressing stem cells located in the bulge area of the hair follicle can give rise to multiple cell types. In the present study, we subcutaneously transplanted red fluorescent protein (RFP)-labeled SK-MEL-5 human melanoma cells into nestin-driven green fluorescent protein...