King University

Combining force and kinematic signals for human-computer interface: insights from cursor control by flexible pressure sensors

Cursor control becomes difficult in space-constrained environments, such as operating portable computers while wearing pressurised gloves. Flexible pressure sensorscan capture fingertip kinematic (centre of pressure, CoP) and force signals within confined spaces, offering a poten...

Coordination Engineering of Cobalt Single-Atom Catalysts for Periodate Activation with Regulated Reactive-Species Production toward Emerging Contaminants Degradation

Abstract Fenton-like reaction of heterogeneous periodate (PI) activation exhibits high efficiency for emerging contaminants degradation due to the production of iodine-centered radicals, and single-atom metal catalysts demonstrate high activity. However, precisely controlling the...

BeyondFreeze Concentration:Interfacial ProcessesShape Cr(VI) Reduction by Organic Acids in Frozen Systems

Abstract Ice-phase Cr(VI) reduction is commonly attributed to freeze concentration and proton enrichment, implicitly assuming solution-like reaction mechanisms. However, this study reveals that interfacial processes serve as a critical complement to freeze concentration and stron...

Prediction andControlling Factors of Macrolithotypesin Deep Coal Reservoirs

Abstract Deep coalbed methane (CBM) in the Ordos Basin is a critical resource for China’s unconventional gas supply. Accurate identification of coal macrolithotypes is essential for reservoir characterization and guiding efficient exploration and development. However, the deep co...

Isomer Effect of Double-Spiro Mechanophores in Polymer Mechanochemistry

Abstract Easy construction of rhodamine spiro rings and diversity of naphthalenediol enable various isomers of the naphthalene-fused double rhodamine structure and provide the possibility to study the structure–performance relationship of double-spiro mechanophores. Herein, we fo...

A Heterogeneous Metal–LigandBifunctional Catalystfor Chemoselective Hydrogenation of α,β-Unsaturated Aldehydes

Abstract The concept of metal–ligand bifunctional catalysts has been extensively explored in homogeneous catalysis, yet it has not been reported in conventional heterogeneous catalysis. Inspired by the outer-sphere hydrogenation mechanism in homogeneous metal–ligand bifunctional...

Freeze–ThawCycles Greatly Affect the ConjugativeTransfer of Antibiotic-Resistant Genes: Effects of the Secretion ofExtracellular Polymeric Substances

Abstract Freeze–thaw (FT) cycle, a ubiquitous and important physical process in natural environments, may influence the horizontal gene transfer (HGT) process of antibiotic-resistant genes (ARGs), yet its impact and underlying mechanisms remain unclear. This study investigated th...

End-to-End Differentiable Learning of a Single Functionalfor DFT and Linear-Response TDDFT

Abstract Density functional theory (DFT) and linear-response time-dependent density functional theory (LR-TDDFT) rely on an exchange-correlation (xc) approximation that provides not only energy but also its functional derivatives, which enter the self-consistent potential and the...

Assessment of masticatory muscle activity and mandibular border movement in skeletal class II malocclusion adolescents with mandibular retrognathia

<title>Abstract</title> Objective To investigate masticatory muscle activity and mandibular border movement in adolescents with skeletal class II malocclusion and mandibular retrognathia and explore the influence of mandibular retrognathia on masticatory system function. Methods...

Two‐Dimensional Conjugated Metal Organic Frameworks with Dual Metal Catalytic Active Sites Enhance POD Activity for Antibacterial Treatment

ABSTRACT The emergence of drug‐resistant bacteria has brought a grand challenge to the treatment of oral ulcers (OUs). Peroxidase (POD) enzymes catalyze the conversion of hydrogen peroxide (H 2 O 2 ) into reactive oxygen species (ROS), offering a promising strategy for treating d...

A Tumor-Microenvironment-Responsive Chemically MaskedIL-2 Prodrug Potentiates PD-1 Checkpoint Blockade andElicits Robust Antitumor Efficacy

Abstract Interleukin-2 (IL-2) is a potent mediator of T-cell activation with significant potential for cancer immunotherapy, yet its clinical utility is severely constrained by its narrow therapeutic window. Here we report a chemically masked IL-2 prodrug (Cm-proIL2) that enables...

Targeting the immune-metabolic axis reverses orthodontics-induced systemic pathology

Orthodontic treatment corrects various craniofacial malformations primarily through triggering active alveolar bone remodeling, however the potential impacts of this intervention on the systemic immune state have long been insufficiently explored. Here, we show that mechanical fo...