Kermanshah University of Medical Sciences

The moderating role of organizational intelligence on the relationship between knowledge management and healthcare service quality in Iranian hospitals

Modern healthcare systems face mounting challenges stemming from technological advancements, rising patient expectations, and the growing imperative to integrate evidence-based data into clinical practice. Although effective Knowledge Management (KM) is widely recognized as essen...

Quercetin biomolecule-stabilized gold nanoparticles: a synthesis-to-biotherapy platform for antibacterial, anti-hemolytic, anti-inflammatory, and anticancer applications

This study aimed to synthesize gold nanoparticles (GNPs) using quercetin (QU) biomolecule as a natural reducing and stabilizing agent and to evaluate its biointerface and biotherapeutic potential. The bio/nano-formulated QU-GNPs with crystalline structure from XRD pattern showed...

Advances in regenerative medicine and their impact on cancer therapy and tumor microenvironment modulation

Regenerative medicine has emerged as a transformative field that can augment cancer therapy by leveraging stem cells, gene therapy, and tissue engineering to address limitations of conventional treatments. This review synthesizes recent advances in cell-based therapies, biomateri...

The role of hSSB1 and hSSB2 in the DNA damage response: mechanisms and implications

Abstract The DNA damage response preserves genome integrity by detecting DNA lesions, activating checkpoint signalling, and coordinating repair with cell-cycle control. Defective or incomplete repair can promote mutation accumulation, chromosomal instability, cancer development,...

Brain MRI Changes Following Continuous Positive Airway Pressure Therapy in Adults with Obstructive Sleep Apnea: A Systematic Review

Abstract Study Objectives Obstructive sleep apnea (OSA) is associated with structural, microstructural, functional, vascular, and metabolic brain alterations. Continuous positive airway pressure (CPAP) is the first-line treatment for OSA, but whether OSA-related abnormalities on...

Complex interactions between miR-107 and PTEN gene expression, more specifically in viral and NASH cirrhosis

Background microRNAs play critical roles in modulating the molecular pathways involved in liver fibrosis. miR-107 has been reported to be elevated in the liver of patients with non-alcoholic fatty liver disease (NAFLD), and it is believed to regulate the PTEN gene, a negative reg...