Kermanshah University of Medical Sciences

Nanoarchitectonics of phenolic acid-functionalized gold nanoparticles: A bioinspired nanoplatform for erythrocyte membrane and protein protection, bacterial and cancerous cellular toxicity

Abstract Ferulic acid-trans form (TFA) was applied for the biosynthesis of gold nanoarchitectonics (TFA-GNPs) as a reducing and stabilizing agent under optimal conditions. The most favorable conditions for this synthesis included a pH of 7, a reaction duration of 4 h, and a tempe...

Typology of learning styles in medical students: a systematic review of 33 countries

Understanding students' learning styles is crucial for guiding the teaching–learning process according to their individual needs and preferences, and for creating effective pedagogical situations. Therefore, this systematic review aimed to identify learning styles in medical stud...

Qualitative exploration of challenges in cardiopulmonary resuscitation within pediatric intensive care units (PICU)

Cardiopulmonary resuscitation (CPR) in the Pediatric Intensive Care Unit (PICU) is a vital, sensitive, and complex process that has a direct impact on patient survival and prognosis. Any disruption during the resuscitation process may lead to irreversible consequences. However, v...

Design and validation of the love in nursing instrument

Abstract Existing instruments designed to measure the construct of love exhibit various limitations or fail to specifically address love within the nursing context. Consequently, there is a distinct lack of a unified, domain-specific tool to evaluate love in the nursing professio...

Association between preoperative hypoalbuminemia and postoperative complications in spinal fusion surgery: an approach- and spinal level-stratified meta-analysis

While hypoalbuminemia is recognized as a risk factor for adverse postoperative outcomes in various surgeries, its specific impact on spinal fusion outcomes has not been systematically synthesized. This meta-analysis aimed to evaluate the association between preoperative hypoalbum...

The moderating role of organizational intelligence on the relationship between knowledge management and healthcare service quality in Iranian hospitals

Modern healthcare systems face mounting challenges stemming from technological advancements, rising patient expectations, and the growing imperative to integrate evidence-based data into clinical practice. Although effective Knowledge Management (KM) is widely recognized as essen...

Quercetin biomolecule-stabilized gold nanoparticles: a synthesis-to-biotherapy platform for antibacterial, anti-hemolytic, anti-inflammatory, and anticancer applications

This study aimed to synthesize gold nanoparticles (GNPs) using quercetin (QU) biomolecule as a natural reducing and stabilizing agent and to evaluate its biointerface and biotherapeutic potential. The bio/nano-formulated QU-GNPs with crystalline structure from XRD pattern showed...

Advances in regenerative medicine and their impact on cancer therapy and tumor microenvironment modulation

Regenerative medicine has emerged as a transformative field that can augment cancer therapy by leveraging stem cells, gene therapy, and tissue engineering to address limitations of conventional treatments. This review synthesizes recent advances in cell-based therapies, biomateri...

The role of hSSB1 and hSSB2 in the DNA damage response: mechanisms and implications

Abstract The DNA damage response preserves genome integrity by detecting DNA lesions, activating checkpoint signalling, and coordinating repair with cell-cycle control. Defective or incomplete repair can promote mutation accumulation, chromosomal instability, cancer development,...

Brain MRI Changes Following Continuous Positive Airway Pressure Therapy in Adults with Obstructive Sleep Apnea: A Systematic Review

Abstract Study Objectives Obstructive sleep apnea (OSA) is associated with structural, microstructural, functional, vascular, and metabolic brain alterations. Continuous positive airway pressure (CPAP) is the first-line treatment for OSA, but whether OSA-related abnormalities on...

Complex interactions between miR-107 and PTEN gene expression, more specifically in viral and NASH cirrhosis

Background microRNAs play critical roles in modulating the molecular pathways involved in liver fibrosis. miR-107 has been reported to be elevated in the liver of patients with non-alcoholic fatty liver disease (NAFLD), and it is believed to regulate the PTEN gene, a negative reg...