Kagoshima University

Holonomy Analysis of Optical-polarization Temperature Trajectories in Stress-induced Ferroelectric SrTiO 3

We develop a data-induced geometric framework for temperature trajectories in optical-polarization data and apply it to temperature-dependent birefringence imaging of stress-induced ferroelectric SrTiO 3 . By treating the measured response as an observable projection of local mat...

Effects of temperature, irradiance and varying light spectral qualities on photochemical efficiency of the edible red alga, Gloiopeltis frutex (Endocladiaceae) from Kagoshima Prefecture, Japan

The effects of temperature and irradiance, including light spectral quality, on the photochemical efficiency of the edible red alga Gloiopeltis frutex (Endocladiaceae) were determined using a pulse-amplitude-modulated (PAM) chlorophyll fluorometer. The temperature response (4–36...

Anti-RANKL antibody treatment mitigates subchondral bone loss and cartilage degeneration without affecting synovial inflammation in a mouse model of rotator cuff tear arthropathy

Aims Enhanced osteoclast activity in subchondral bone is implicated in osteoarthritis (OA) progression, but the contribution of osteoclasts versus synovial inflammation in cuff tear arthropathy (CTA) remains unclear. This study investigated whether inhibition of osteoclasts using...

Observed weakening of the Kuroshio driven by the East Asian winter monsoon under ongoing climate warming

Abstract Western boundary currents are generally thought to respond to global warming through basin-scale wind forcing and ocean stratification, yet the role of local winds remains unclear. Here, we investigate changes in the Kuroshio under ongoing climate warming using satellite...

Rapid genome-wide purging following tsunami-induced hybridization in a stickleback population

Speciation is the process by which barriers to gene flow evolve between populations. As speciation approaches completion, genome-wide divergence can be maintained in the face of hybridization. Because real-time observations of genomic changes following hybridization in natural po...

Community structure of freshwater Macrobrachium shrimps (Decapoda: Palaemonidae) in a subtropical river, Iriomote Island, southern Japan

We examined the spatial and seasonal drivers of Macrobrachium shrimp community structure in the freshwater reaches of the Yutsun River, northern Iriomote Island, Japan. From January to December 2019, we conducted monthly visual censuses at seven stations spanning 300 m intervals,...

Triangulating Evidence on Serum Uric Acid and Cancer Risk: Consistent Inverse Associations With Lung Cancer

ABSTRACT We examined the association between serum uric acid (UA) levels and cancer incidence through a conventional observational and two‐sample Mendelian randomization (MR) study in the same population (triangulation). We followed 13,695 individuals aged 35–69 years for cancer...

Non-destructive approach using micro-CT for understanding the strategy of mesoparasitism of the genus Cardiodectes (Copepoda: Siphonostomatoida: Pennellidae) on marine fishes, with a new species description from coastal waters of the Ryukyu Islands, the western North Pacific

Abstract A new species of pennellid copepod (Siphonostomatoida), Cardiodectes laybackinabaueroides sp. nov., is described based on postmetamorphic adult females collected from the coastal waters of the Ryukyu Islands, western North Pacific, Japan. The new species differs from oth...

Tail-degloving and cold storage facilitate primary cell culture from wild-caught rodents

The use of wild rodents as biological resources is hindered by the difficulties of live transport and primary culture contamination caused by skin bacteria. To address this, we developed a "tail-degloving" method to physically remove the contaminated external integument. Using th...

Temporal change in mass eruption rate estimated from co-eruptive seismograms during 2014–2018 eruption at Sinabung Volcano, Indonesia

Abstract An effusive eruption occurred at Sinabung volcano, Indonesia, from December 2013 to February 2018. The eruption peaked with violent pyroclastic density currents (PDCs) and a lava flow in the first three months of 2014 and then gradually declined. After the lava flow acti...

Exploratory proteomic analysis of idiopathic pulmonary fibrosis and fibrotic hypersensitivity pneumonitis using data-independent acquisition

Idiopathic pulmonary fibrosis (IPF) and fibrotic hypersensitivity pneumonitis (fHP) are two distinct interstitial lung diseases often showing similar clinical features, making differentiation challenging. Precise diagnosis is essential because treatment strategies for these condi...

Intensive preoperative glucose management including hospitalization is associated with lower surgical site infection in patients with diabetes: A retrospective multicenter observational study

AIMS: Perioperative glycemic control reduces surgical complications, such as surgical site infection (SSI), but evidence regarding the effect of preoperative hospitalization for this purpose is limited. In Japan, some patients with diabetes are admitted for 1-2 weeks before surge...

Stolephorus lotus, a New Anchovy (Teleostei: Clupeiformes: Engraulidae) from the Northern Territory, Australia

Babu Rao, 1966, in having a long maxilla (posterior tip just reaching or extending slightly beyond the posterior margin of the opercle), indented posterior preopercular margin, anal fin with 16-18 branched fin rays, and 21-23 lower gill rakers, and lacking a predorsal scute and p...

Evaluation of clinical prognostic factors for radium-223 therapy in castration-resistant prostate cancer with bone metastases: the KYUCOG-1901 study

We evaluated clinical factors associated with symptomatic skeletal events (SSEs), radiographic progression-free survival (rPFS), and overall survival (OS) in patients with metastatic castration-resistant prostate cancer (mCRPC) and bone metastases treated with radium-223 (Ra-223)...

GH172 Difructose Dianhydride I Synthase: A Two‐Stepped Journey via Glycosylation and Cyclization Using QM/MM Metadynamics

ABSTRACT The difructose dianhydride I synthase/hydrolase catalyzes the reversible transformation of inulobiose into difructose dianhydride I, a component of caramel. The proposed reaction mechanism of such a transformation consists of a glycosylation step followed by a cyclizatio...

Safety of Endoscopic Ultrasound-Guided Biliary Drainage in Patients with Distal Malignant Biliary Obstruction with Large-Volume Ascites

Background/Aims: The safety and efficacy of endoscopic ultrasound-guided biliary drainage (EUS-BD) in patients with large-volume ascites (LVA) remain unclear. We aimed to evaluate the safety of EUS-BD in patients with distal malignant biliary obstruction complicated by LVA. Metho...

Defining leadership competencies for rural community-based medicine: a Delphi study and field-based curriculum evaluation for undergraduate medical students

Abstract Background Leadership is essential in community-based medicine, yet inconsistently taught in Japan’s undergraduate medical curricula. This study aimed to: (1) identify essential community-based leadership competencies using a Delphi approach, (2) develop and pilot a stru...

Housing environments link egg taste through metabolic alterations in laying hens

Farm animal welfare is increasingly recognized as a core component in sustainable protein production. The transition to welfare-friendly housing systems—such as from cage to cage-free systems for laying hens—promotes the expression of motivated behaviors by providing greater spac...

Relationship between initial dose, dose intensity, and survival in unresectable pancreatic cancer treated with nanoliposomal irinotecan, fluorouracil, and folinic acid

Abstract While nanoliposomal irinotecan with fluorouracil and folinic acid (NFF) is a standard second-line regimen for unresectable pancreatic cancer (uPC) after gemcitabine-based therapy, the effects of initial dosing and relative dose intensity (RDI) in routine practice are unc...

Using Texture Analysis of US Images to Differentiate Late Neck Lymph Nodes Metastasis to Nonmetastasis in Oral Squamous Cell Carcinoma

ABSTRACT Purpose The purpose of this study was to perform texture analysis of late neck lymph nodes metastases (NLNMs) and non‐NLNMs in postoperative oral squamous cell carcinoma (SCC) on ultrasound (US) images and identify the optimal texture features for distinguishing these ne...