Jimma University

Collaborative clinical research ethics and regulatory governance in Sub-Saharan Africa: Gaps, challenges and implications

Although some countries in sub-Saharan Africa have strengthened their systems and reached WHO GBT Maturity Level 3, important gaps remain. Addressing these gaps is critical for strengthening clinical research oversight and preparedness. This open letter highlights that ethics and...

Determinants of tuberculosis treatment outcomes among TB/HIV co-infected patients in Gambella refugee camps, Western Ethiopia: a case–control study

Abstract Background TB and HIV co-infection remains a major global public health problem and a leading cause of morbidity and mortality in Ethiopia, one of the 30 high TB/HIV burden countries. Co-infection compromises immune function, thereby increasing the risk of poor treatment...

Optimization of surface water treatment using indigenous biocoagulants ( Opuntia ficus-indica and Moringa stenopetala ): a central composite design approach

ABSTRACT The growing concerns over the economic, health, and environmental impacts of traditional chemical coagulants have sparked a global interest in finding more sustainable alternatives for water treatment. This study explores and compares two locally available Ethiopian plan...

Modeling of wetting-state evolution in polypropylene-stearic acid functionalized nanostructured superhydrophobic coatings

Superhydrophobic coatings often lose their water-repellent properties after repeated abrasion and environmental exposure, creating a need for reliable methods to predict coating durability. This study developed a machine learning-based framework to predict the water contact angle...

Clinical validation of an ultra-low-cost smartphone-based offline AI platform for glaucoma screening in low-resource settings

Glaucoma is one of the leading causes of irreversible blindness worldwide, affecting more than 76 million people, with prevalence expected to increase substantially in the coming decades. Early detection is critical to prevent vision loss; however, access to ophthalmologists and...

Trace metal accumulation in automotive garage soils of Jimma Town Ethiopia and its potential health implications

Abstract Garages generate waste streams—including used oils, metal fragments, brake and tire debris, and fluid spills—that introduce trace metals into surrounding soils. This study quantified chromium (Cr), zinc (Zn), and copper (Cu) in topsoils from six garages (G1-G6) in Jimma...

Concurrent tuberculous and cryptococcal meningitis with hydrocephalus in an HIV- negative patient: a fatal case report

Concurrent central nervous system infections caused by Mycobacterium tuberculosis and Cryptococcus neoformans are exceedingly rare, particularly in HIV-negative (Human Immunodeficiency Virus) immunocompetent individuals, and present significant diagnostic and therapeutic challeng...

Sexual, mental, and multidimensional determinants of health-related quality of life in Parkinson's disease using the revised Wilson and Cleary model

According to the World Health Organization (WHO), the global disability burden associated with Parkinson’s disease (PD) has increased by 81% in recent decades. Consequently, health-related quality of life (HRQoL) has become a crucial patient-reported outcome measure. Due to the m...

Optimizing soil fertility, malt barley yield, and economic returns through integrated compost and nitrogen fertilization: yield, soil, and economic analysis in the Ethiopian highlands

Abstract Malt barley is an important crop in the Ethiopian highlands, where productivity is challenged by soil fertility decline, inappropriate agronomic practices, and high dependence on inorganic fertilizers. This study evaluated the effects of compost and inorganic N fertilize...

Effects of multicomponent lifestyle interventions on body composition and lipid profiles in Breast cancer: a systematic review and meta-analysis

Individuals with breast cancer often experience negative changes in anthropometry, body composition, and lipid profiles, which increase their cardiovascular and metabolic risk. Although exercise, nutrition education, and psychosocial interventions are each beneficial individually...

Urban green spaces as nature-based solutions for carbon storage and human thermal comfort: evidence from Jimma City, Ethiopia

Urban green spaces provide critical ecosystem services, including carbon storage and thermal regulation, yet their condition remains poorly quantified in many rapidly urbanizing African cities. This study assessed the potential of urban green spaces as nature-based solutions for...

Prevalence and determinants of anxiety and depression among children and adolescents undergoing cancer treatment at a tertiary hospital in a resource-limited setting

Childhood cancer significantly impacts the mental health and overall well-being of children and adolescents. Mental health issues, such as depression and anxiety, are common among these children. These conditions can lead to long-term consequences, including poor psychosocial fun...

Optimizing drip irrigation density enhances growth, yield, physiology, and antioxidant capacity of Korean strawberry ‘Kuemsil’ in recycling hydroponics

Efficient irrigation management is crucial for improving water-use efficiency and maintaining high productivity in controlled-environment strawberry cultivation. This study evaluated how different drip irrigation densities influence the growth, physiological responses, yield, fru...

Climate change adaptation strategies of rural women-headed households in southwestern Ethiopia

Climate change imposes severe challenges on smallholder farmers in Ethiopia, with women-headed households being particularly vulnerable. This study assessed climate change adaptation strategies among 304 women-headed households in Omo Nada district, southwestern Ethiopia, and ana...

Spatiotemporal variability and trends of precipitation, temperature, and evapotranspiration in the Muger sub-basin of the Abbay basin Ethiopia

Abstract This study used time series data from 1980 to 2022 to investigate spatiotemporal changes and trends of precipitation, temperature, and evapotranspiration in Muger sub-basin. The coefficient of variation (CV), precipitation concentration index (PCI), and seasonality index...

Collateral damage of the EU deforestation regulation on commodity supply chains in cocoa, coffee, palm oil, soy, and cattle value chains

The European Union Deforestation Regulation (EUDR), formally adopted as Regulation (EU) 2023/1115, seeks to reduce global deforestation by requiring deforestation-free and legally compliant supply chains for commodities including cocoa, coffee, palm oil, soy, cattle, wood, and ru...

A systematic literature review of blue ocean strategy (BOS) as a reconstructive approach to the competitive advantage

This research conducted a systematic literature analysis of empirical studies published between 2019 and 2025 to investigate the contemporary function of blue ocean strategy (BOS) in attaining competitive advantage. In accordance with PRISMA 2020 guidelines, the document consolid...

The impact of blue ocean strategy’s ERRC grid on community engagement in higher education at Puntland state university in Somalia

The study assesses the extent to which Eliminate-Reduce-Raise-Create (ERRC) dimensions in the blue ocean framework associate with community engagement at Puntland State University (PSU) in Somalia. Specifically, it evaluates the effectiveness of the ERRC grid in strengthening uni...

Machine learning for early prediction of preterm birth

Abstract Background Preterm birth (PTB), defined as delivery before 37 completed weeks of gestation, remains a major cause of neonatal mortality and long-term morbidity worldwide. Conventional risk assessment strategies, including cervical length measurement and biomarker-based s...

Evaluation of undercut depth for flexible pavement on unsuitable tropical red soils using finite element method

Due to the lack of a reliable classification system and inadequate evaluation of their engineering properties, undercut depth is recommended for tropical red soils when used in flexible pavement construction. The aim of this study is to determine the ideal depth for subgrade unde...