Istanbul Technical University

Amantadine, donepezil and memantine associated arrhythmia in an elderly patient

<title>Abstract</title> <bold>2.1 Case İnformation</bold> A 78 years old man was referred to the cardiology clinic because of mild dyspnea.Electrocardiography (ECG) showed sinus bradycardia at a rate of 59 beats/min, right bundlebranch block (RBBB), first-degree AV block, and nor...

Modeling the combined effects of the 2023 Türkiye–Syria earthquake and an Atmospheric River event on landslide hazard

Abstract. The 6 February 2023 Türkiye–Syria earthquake doublet triggered thousands of coseismic landslides. On 14–15 March, an Atmospheric River (AR) delivered up to 183 mm of rainfall across the seismically weakened region, triggering hundreds of additional landslides and debris...

The impact of Socratic method on middle school students achievement in non-routine problem solving and their attitudes toward mathematical problem solving

Non-routine problems play a significant role in mathematics learning due to their potential to foster students’ reasoning, inquiry, and critical thinking skills. Students, however, often experience difficulties in solving these problems and may experience negative attitudes towar...

PET Micro/Nanoplastic–Tetracycline Co-Exposure in Defibrinated Blood: Exploratory Spectroscopic, Redox, and Escherichia coli Responses

Previous studies have indicated that polyethylene terephthalate (PET) micro/nanoplastics (MNPs) may coexist with antibiotics in environmental and biological matrices; however, their combined behavior in blood remains insufficiently characterized. This study examined PET MNPs prep...

Comparative Transcriptomic Analysis of Neurodegeneration and Viral Infection: A Multi-Method Validation Framework

AbstractParkinson's disease and influenza virus infection present with entirely different clinical pictures, yet both have been linked to shared inflammatory and neuroimmune mechanisms, an interest dating back to post-encephalitic parkinsonism following the 1918 influenza pandemi...

In Situ Effects of 4,6-α- and 4,3-α-Glucanotransferases During Sourdough Fermentation: Assessing Microbial Community Dynamics, Bread Glycemic Index, Staling, and Texture

Although some lactic acid bacteria species harbor genes encoding α-glucanotransferases (4,6-α-GTase and 4,3-α-GTase), the technological and functional implications of these enzymes within sourdough ecosystems remain poorly understood. This study investigated the effects associate...

Greater Mediterranean Diet Adherence Is Associated with Lower Odds of Chronic Migraine: A Retrospective Observational Study

Background: Dietary factors may influence migraine burden, but the relationship between Mediterranean diet (MD) adherence and migraine chronicity remains unclear. This study aimed to investigate whether higher MD adherence is associated with a less severe migraine phenotype, part...

Determination of main components by capillary electrophoresis and antioxidant activities in anatolian royal jellies: discrimination by principal component analysis

Royal jelly (RJ), a secretion of worker honey bees, is a nutritionally valuable bee product known for its bioactive properties. Different regions offer distinct floral sources that bees feed on, resulting in a unique composition of the RJ they produce. Moreover, certain component...

Evaluating the psychosocial benefits of mindfulness-based art therapy for breast cancer patients: a preliminary study

Abstract This preliminary study evaluates the psychosocial benefits of mindfulness-based art therapy (MAT) for breast cancer patients. A quasi-experimental design was used with 14 participants in the experimental group and 15 in the control group. The experimental group attended...

omicau benchmark protocol: a leakage-safe, compute-efficient evaluation of multi-omics audit and fusion workflows

This working paper and protocol prospectively specifies an independent, compute-efficient benchmark of omicau, a multi-omics audit and fusion workflow. Simulated datasets are independent experimental units evaluated with one frozen five-fold cross-validation partition. Real cohor...

omicau benchmark protocol: a leakage-safe, compute-efficient evaluation of multi-omics audit and fusion workflows

This working paper and protocol prospectively specifies an independent, compute-efficient benchmark of omicau, a multi-omics audit and fusion workflow. Simulated datasets are independent experimental units evaluated with one frozen five-fold cross-validation partition. Real cohor...