IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola

Topical Finasteride 0.25% Solution for Female Pattern Hair Loss (FPHL) in Postmenopausal Women: A 52‐Week Retrospective Observational Study

BACKGROUND: Female pattern hair loss (FPHL), characterized by progressive follicular miniaturization, is the most common cause of hair thinning in women and increases in prevalence after menopause. While topical minoxidil is approved for FPHL, clinical response is variable. Oral...

Reducing antibiotic burden in gram-negative bacteraemia: duration optimization and early oral transition

PURPOSE OF REVIEW: Gram-negative bloodstream infections have traditionally been managed with prolonged and intravenous antibiotic therapy. This review aims to summarize the evidence supporting strategies to reduce antibiotic burden through shorter treatment durations and/or oral...

A Descriptive Observational Study of Real-Time TDM-Guided Aggressive PK/PD Target Attainment and Microbiological/Clinical Outcome in Patients with Stenotrophomonas maltophilia Bloodstream Infections and/or Pneumonia Treated with Continuous Infusion Cefiderocol

Objectives: To assess whether attaining an aggressive pharmacokinetic/pharmacodynamic (PK/PD) target with continuous infusion (CI) cefiderocol could be an effective strategy for managing documented bloodstream infections (BSIs) and pneumonia caused by Stenotrophomonas maltophilia...

Renal Artery Occlusion After Standard Endovascular Aneurysm Repair: Incidence, Mechanisms, and Individualized Management

Background/Objectives: Direct renal artery compromise after standard endovascular aneurysm repair (EVAR) is rare and may result from mechanical ostial coverage or atheroembolism. We estimated its incidence and described mechanism-specific management and renal outcomes. Methods: W...

Intraretinal Hyperreflective Foci as an OCT Feature Associated With Retinal Remodeling After Macular Hole Closure

Purpose: To investigate intraretinal hyperreflective foci (HF) within the foveola in the healing process following surgical closure of full-thickness macular holes (FTMHs), using lamellar macular holes (LMHs) and vitreomacular traction (VMT) as comparisons. Methods: Analysis of s...

Tools for providing information to patients about high-tech medical resources for treatment of cancer

BACKGROUND AND PURPOSE: High-tech medical resources play an increasingly important role in cancer diagnosis and treatment. However, accessing information about these technologies remains challenging due to their complexity and a lack of clear information pathways to obtain reliab...

Accuracy of percutaneous ultrasound-guided needle biopsy of abdominal lymph nodes for the diagnosis of malignant disease.

The differential diagnosis of suspected neoplastic disease involving deep lymph nodes remains challenging, particularly in the abdomen, where biopsies are technically more complex and associated with higher procedural risks. The present retrospective single-center study aimed to...

Predictors of Early Posttransplant Complications and Clinical Outcomes in Kidney Transplant Recipients Aged ≥65 y.

Background: Older adults represent a growing proportion of kidney transplant (KT) recipients, but early posttransplant morbidity remains substantial. We aimed to identify pretransplant factors associated with a complicated early posttransplant course in recipients aged ≥65 y and...

Incidence and Predictors of Complications After Transcatheter Aortic Valve Implantation According to VARC‐3 Criteria: A Systematic Review and Meta‐Analysis

BACKGROUND: Despite continuous advancements in devices and techniques, transcatheter aortic valve implantation remains associated with complications impacting outcomes. In 2021, the Valve Academic Research Consortium (VARC) introduced the VARC-3 criteria to better classify proced...

Heart Donation After Controlled Circulatory Death in Noncardiac Surgery Hospitals With a Mobile Heart Team: A Case Series From an Italian Regional Program and Integrated Review of the Literature

ABSTRACT Controlled donation after circulatory death (cDCD) with thoracoabdominal normothermic regional perfusion (TA‐NRP) has emerged worldwide as a strategy to expand the heart donor pool. In Italy, however, its implementation is constrained by a particularly restrictive settin...

CEUS for the diagnosis of acute graft pyelonephritis in renal transplant recipients

Abstract Purpose Acute graft pyelonephritis (AGPN) is a clinically relevant complication in renal transplant recipients, in whom diagnosis may be challenging because of nonspecific clinical and conventional ultrasound findings. Contrast-enhanced ultrasound (CEUS) enables real-tim...

Comparative Efficacy Of Different Computer-Aided Detection Products in Colonoscopy: A Network Meta-Analysis Of Randomized Controlled Trials.

Background and aims: Multiple computer-aided detection (CADe) systems have been developed to improve adenoma detection during colonoscopy, but their comparative efficacy and consistency of effect remain uncertain. This network meta-analysis aimed to compare the efficacy of differ...