International Centre for Genetic Engineering and Biotechnology

Immunologic insights into the critical epitopes of HIV-1 and structure-based characterization of cross-reactive antibodies

Abstract HIV-1 escape from neutralizing antibodies even in the presence of strong host immunity is associated with variations in envelope proteins that drive antigenic diversification. The virus exploits the error-prone nature of reverse transcriptase and the high mutation rate a...

Exploring the dynamics of symbiont Enterobacter aerogenes expressing Cry1Ac for potential biocontrol of Helicoverpa armigera

Paratransgenesis, the use of genetically modified symbiotic microbes to deliver bioactive molecules, offers a promising strategy for sustainable pest management. However, the colonization dynamics and ecological interactions of such engineered microbes remain insufficiently under...