Integrated Chinese Medicine (China)

Vitamin D in spine disorders: mechanisms, clinical evidence, and translational gaps—a narrative review

Vitamin D has been increasingly implicated in the pathophysiology of spine disorders, yet its clinical utility remains uncertain. Across a broad spectrum of conditions, including intervertebral disc degeneration, chronic low back pain, lumbar spinal stenosis, spinal deformities,...

Comparative Efficacy of Body Acupuncture, Electroacupuncture, and Auricular Acupuncture in Stroke Rehabilitation

OBJECTIVE: To compare the efficacy of body acupuncture, electroacupuncture, and auricular acupuncture on motor, functional, and neurological recovery after stroke. DESIGN: Systematic review and meta-analysis of randomized controlled trials. Eligible studies enrolled adult stroke...

Early oseltamivir initiation and influenza outcomes in kidney transplant recipients: a multicenter real-world study

Influenza infection poses a significant clinical threat to kidney transplant recipients due to their immunocompromised status. Although current guidelines recommend early antiviral therapy, real-world evidence supporting the effectiveness of oseltamivir, particularly regarding th...

MXene-Based Conductive Microneedle Patch Promotes Diabetic Wound Healing by Regulating Oxidative Stress and Immune Microenvironment

Abstract Excessive reactive oxygen species (ROS) generation and the release of inflammatory mediators create a pathological microenvironment in diabetic wounds, severely impairing the healing process. Coupling endogenous electric fields has shown great therapeutic potential for i...

Associations of outdoor artificial light at night with type 2 diabetes and metabolic syndrome among Chinese adults

This study investigated the associations between outdoor artificial light at night (ALAN) and type 2 diabetes (T2DM) and metabolic syndrome (MetS) and aimed to characterize the dose-response relationships and potential exposure thresholds. This cross-sectional study included 57,8...

“Jun-Chen-Zuo-Shi” - the Chinese medical perspective on clinical oncology nutritional therapy

Abstract Cancer-associated malnutrition and cachexia are common, clinically consequential syndromes that compromise treatment tolerance, increase postoperative and therapy-related complications, diminish quality of life, and shorten survival. Nutritional therapy is therefore incr...

Association between platelet-to-white blood cell ratio trajectories and all-cause mortality in critically ill patients with acute exacerbation of chronic obstructive pulmonary disease: a retrospective cohort study

AECOPD is a leading cause of ICU admission and death in patients with COPD, yet readily accessible biomarkers for dynamic risk stratification remain scarce. The platelet-to-white blood cell ratio (PWR) is a promising inflammatory marker reflecting inflammatory burden and regenera...