Instituto Federal de Educação, Ciência e Tecnologia de Pernambuco

Upregulation of cellular exhaustion-related genes and CD4 + T cell disturbances in immunological non-responders on antiretroviral therapy

Abstract Antiretroviral therapy suppresses HIV replication, but 10–40% of people living with HIV do not reconstitute CD4 + T cell counts despite viral suppression. Cellular exhaustion and alteration in the frequency of CD4 + T cell subsets are mechanisms involved in immunological...

Absolute Primary Nanothermometry Using Individual Stark Sublevels of Rare-Earth-Doped Crystals

Abstract We present two independent optical methods for absolute primary thermometry using rare-earth-doped nanoparticles. Both approaches rely exclusively on the internal energy levels and population dynamics of the dopant ions, eliminating the need for external temperature refe...

Longitudinal gradients modulate the distribution, composition, and ecological risk of microplastics in a neotropical public water supply reservoir

Abstract Microplastics (MPs) contamination was assessed in the water and surface sediment in the upstream, dam, and downstream zones of the Tapacurá Reservoir, a tropical public water supply system in northeastern Brazil, over the course of four sampling campaigns. MPs were detec...