Instituto de Biofísica Carlos Chagas Filho

Tubastraea coccinea (Cnidaria: Anthozoa) is the globally dispersed species of Sun Coral

Species of the genus Tubastraea (sun corals) have dispersed globally over recent decades, but morphological trait identification has led to taxonomic confusion, with multiple authors proposing conflicting species identifications due to high morphological plasticity and overlappin...

Translational control of microglial metabolism, inflammatory responses, and survival by the eIF4E-binding proteins

In Alzheimer’s disease (AD), activation of the mechanistic target of rapamycin (mTOR) pathway promotes microglial neuroprotective functions by engaging multiple cell receptors. However, the relevant downstream effectors are not fully understood. mTOR complex 1 (mTORC1) promotes m...

Endocrine and systemic toxicity of pyriproxyfen in adult female zebrafish: disruption of the HPT axis and peripheral organ impairments

Endocrine-disrupting chemicals (EDCs) can destabilize the hypothalamic-pituitary-thyroid (HPT) axis, a fundamental regulator of vertebrate development and metabolism. Pyriproxyfen (PPF), a juvenile hormone analog widely utilized in vector control, is recommended by the World Heal...