Institution
Institute on Aging
Recent research
- BiologyOpen access
Sex-specific biological aging clocks across organs and omics
Sex differentially shapes aging, neurodevelopment and neurodegenerative diseases such as Alzheimer’s disease (AD). However, most biological aging clocks (artificial intelligence-predicted age minus chronological age) were trained on sex-pooled samples and implicitly assume sex in...
- Health & MedicineOpen access
Public policies governing U.S. nursing homes emphasize resident rights, autonomy, and person-centered care, yet translating these principles into everyday practice remains challenging – particularly for residents living with dementia whose preferences involve perceived risk. Regu...
- BiologyOpen access
Background: Hearing loss is experienced by two-thirds of hospitalized older adults and is associated with poor access to healthcare and negative health outcomes. Personal hearing amplifiers (PHAs) are evidence-based assistive devices provided in many hospitals to improve accessib...
- BiologyOpen access
Robust inference and correlates from genetic associations with personality
Personality traits describe stable differences in how people think, feel and behave, and how they interact with and experience their social and physical environments1,2. Many questions remain unanswered about associations between DNA and personality traits, such as their robustne...
- Health & MedicineOpen access
Health-related quality of life reflects individuals’ perceptions of how a health condition affects their physical, psychological, and social functioning. Amid increasing pressures on primary care systems, people living with dementia are presenting more frequently to hospital sett...