Hubei University of Technology

Explainable machine learning for identifying nonlinear associations between street vitality and the built environment in a Historic District

Historic districts exhibit fine-grained spatial variation, while street vitality may relate nonlinearly to the built environment. Using 213 micro-sampling points in the Lihuangpi Road Historic District, Wuhan, this study integrates heritage location, functional facilities, transp...

Physical Activity and Depressive Symptoms in Guangdong University Students: A Cross-Sectional Moderated Serial Indirect-Association Model Involving Self-Esteem, Positive Psychological Capital, and Perceived Social Support

Background: This cross-sectional study examined whether physical activity was indirectly associated with depressive symptoms through self-esteem and positive psychological capital and whether these associations varied by perceived social support. Methods: Data from 473 students a...

A Novel Acoustic Diffraction Search Algorithm for Global Path Planning of Orchard Transport Robots

A novel heuristic search algorithm, the Acoustic Diffraction Search Algorithm (ADSA), is proposed to address the global path planning problem for orchard transport robots. By simulating the diffraction characteristics of acoustic waves around obstacles, ADSA constructs a search m...

PROTAC-Loaded Nanoparticles Induce a “ROS Storm” through Targeted Degradation of GPX4 in Combination with a Mild Photothermal/Fenton-like Reaction for the Treatment of Triple-Negative Breast Cancer

Abstract Proteolysis-targeting chimeras (PROTACs) are a promising therapeutic approach for degrading disease-causing proteins. However, they often encounter limitations in in vivo applications due to poor solubility, low cellular permeability, unfavorable pharmacokinetics, and mo...

Safety evaluation of new energy three-electric systems using enhanced physics-informed neural networks

Accurate safety-state measurement of the three-electric system in new energy vehicles is essential for ensuring reliable and secure operation. This paper proposes an artificial-intelligence-assisted safety measurement framework that integrates a searchable encryption mechanism wi...

Interactions between lactobacillus and yeast: A recent update

Abstract Lactobacillus and yeast are microorganisms widely distributed in nature. Their interactions significantly impact fermentation processes, human health, and medical care. However, there is a lack of a systematic summary of the characteristics of these interactions, and the...

Phosphorylated STYK1 Promotes Gemcitabine Resistance via Autophagy‐Mediated Cancer Stemness in Pancreatic Cancer

ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies, with gemcitabine resistance remaining a major clinical challenge. Although cancer stemness and autophagy have both been implicated in PDAC chemoresistance, the mechanism by which their crosst...

Engineering visual realism in pureed foods for dysphagia care

While texture modification ensures safe swallowing in dysphagia, homogeneous purees often compromise visual appeal. Treating shaping as the core design objective, this review evaluates established methods for engineering visual realism in pureed foods against available evidence,...

Orientation-Specific Multi-Objective Optimization of Building Envelopes for University Library Reading Spaces: A Design Framework Based on Field-Calibrated Simulation and Hierarchical Decision-Making

University library reading spaces face high occupancy and summer cooling demand, making envelope design critical to thermal comfort, energy use, and daylighting. Existing retrofits use uniform window-to-wall ratio (WWR) and shading but seldom consider orientation-dependent photot...

Identification and Characterization of a Previously Uncharacterized Metagenome-Derived Chitinase and Its Application in N -Acetyl- d -Glucosamine Production from Crayfish Shell Waste

Abstract The generation of agricultural and food-processing byproducts has increased rapidly, highlighting the importance of their high-value utilization. In this study, a putative chitinase gene was identified from a metagenome-assembled genome. The enzyme plays a key role in ch...

Circadian photoreceptor CRYPTOCHROME promotes wakefulness under short winter-like days via a GABAergic circuitry

A cardinal symptom of seasonal affective disorder (SAD, also known as winter depression) is hypersomnolence, while the cause of this ‘winter sleepiness’ is not known. Here, we found that lack of the circadian photoreceptor cryptochrome ( cry ) leads to increased sleep under short...

A Fine-Grained Image Dataset of Gold and Silver Artifacts from the Tomb of Prince Liangzhuang and Preliminary LoRA-Based Generation Experiments

The digital preservation of cultural heritage is evolving from static archiving towards intelligent creation. As representative examples of early Ming Dynasty gold and silver craftsmanship, the gold and silver artifacts from the Tomb of Prince Liangzhuang, with their complex craf...

Formation and Stability of Food Emulsions: A Review through the Lens of the Oil Phase

ABSTRACT Emulsions serve vital roles in the food industry, including structural design and delivery of functional components. As thermodynamically unstable systems, emulsions undergo various destabilization processes over time. Therefore, understanding the instability mechanisms...

Natural pigment-based semiconductor isomers as interfacial layers in organic photovoltaic devices

Purpose This study aims to develop bio-based interfacial materials for organic photovoltaic applications by engineering carotenoid-derived molecular frameworks with favorable energy level alignment and enhanced light-harvesting capability. Design/methodology/approach Three diphen...

Near-infrared optical communication via deep learning-enhanced computational temporal ghost imaging in fog scattering environments

Fog scattering is one of the major factors limiting the performance of near-infrared optical communication (NIRC) systems, since it causes severe attenuation of optical signals. In this work, a NIRC system employing computational temporal ghost imaging (CTGI) is established based...

Thermal response and inlet water temperature estimation for a geothermal bridge deck deicing system

Shallow geothermal energy provides a low-carbon approach to winter bridge-deck heating, but methods for matching heat-supply parameters to meteorological and icing loads remain limited. Field thermal-response tests were conducted on a demonstration bridge in Wuhan, China, and the...

Asymmetric Modality Domain Randomization for Drone-Based RGB–Thermal Tiny Person Detection Under Controlled Synthetic Sensor Shifts

Drone-based red–green–blue (RGB)–thermal tiny person detection must account for the different appearance statistics of visible and thermal sensing. We propose Asymmetric Modality Domain Randomization (AMDR), a training-only strategy that applies modality-conditioned perturbations...

State-bounded directional accumulation in post-liquefaction sand: A hypoplastic formulation for asymmetric cyclic deformation

Experiments on saturated sand show finite, bilateral post-liquefaction strain accumulation with a larger strain excursion on the triaxial-extension (TE) than on the triaxial-compression (TC) side, whereas existing constitutive treatments still struggle to reproduce this asymmetri...

Direct Regeneration of Spent LiFePO 4 Cathodes by Liquid‐Phase‐Mediated Reconstruction

Directregeneration of spent LiFePO 4 (S‐LFP) cathodes is imperative for sustainable battery recycling, yet it remains severely hindered by inherent structural degradation, specifically lithium depletion and irreversible Fe 3+ formation. Herein, we propose a facile, one‐step liqui...

Federated Multi-Label Feature Selection via Anchor-Guided Frequency-Domain Optimization Algorithm

Multi-label text feature selection aims to identify compact and discriminative feature subsets for documents associated with multiple correlated labels. In federated environments, this task is further complicated by high-dimensional search spaces, non-independent and non-identica...