Institution
Hospices Civils de Lyon
Recent research
- BiologyOpen access
Genetics in Heterotaxy: A Case Series and Literature Review on DNAH9 , PKD1L1 , MMP21 , and GDF1
Heterotaxy (HTX) is a rare condition characterized by complex congenital heart defects and a wide spectrum of extracardiac abnormalities that significantly impact survival. While molecular diagnosis is essential for clinical management, next-generation sequencing (NGS) currently...
- Health & MedicineOpen access
Sepsis-induced capillary leak is a major contributor to circulatory dysfunction and tissue edema, yet remains therapeutically unaddressed: numerous interventions showing promise in preclinical models have failed to demonstrate clinical efficacy. This systematic review aimed to ch...
- Health & Medicine
Adrenaline Use and Request for Emergency Medical Assistance to Manage Food Anaphylaxis
Summary Adrenaline was rarely used, medical assistance being requested in two thirds of anaphylaxis cases. Medical assistance request was less frequent if milder or no cardiovascular anaphylaxis symptoms.
- Health & Medicine
Imaging in France: 2026 Update
France has seen significant advancements in radiology in recent years, driven by innovations in research and clinical practice. French groups have developed innovative imaging techniques and artificial intelligence applications in the field of diagnostic imaging and interventiona...
- Health & MedicineOpen access
Occupational hazards in hip and knee adult reconstruction surgery
Aims: Adult reconstruction surgeons face unique occupational challenges during joint arthroplasty procedures, including sustained physical demands, ergonomic strain, noise exposure, and psychological pressure from high patient expectations. This systematic review aimed to synthes...
- Health & MedicineOpen access
ABSTRACT Introduction Co‐use of tobacco and cannabis is common among young adults and is associated with higher dependence and quitting difficulties. Little is known about the preference for simultaneous or sequential dual cessation in this population. We aimed to explore prefere...
- Health & MedicineOpen access
A limited subset of people living with type 1 diabetes (T1D) is affected by extreme glycemic lability and frequent unpredictable severe hypoglycemia, significantly impairing quality of life and associated with higher morbidity, mortality, and healthcare costs. Islet transplantati...
- Health & Medicine
The Orbitofrontal Expansion for Extending Nasoseptal Flap Reach in the Frontal Sinus
Abstract Skull base defects involving the superior and lateral posterior table of the frontal sinus are challenging to reconstruct due to limited surgical access and restricted reach of available reconstructive options. External approaches are often required, increasing morbidity...
- Health & MedicineOpen access
Vancomycin optimised dosing regimens for critically ill patients receiving renal replacement therapy
Optimal dosing of vancomycin in critically ill patients receiving renal replacement therapy (RRT) is uncertain due to high pharmacokinetic variability. We aimed to develop individualised vancomycin dosing recommendations that optimise efficacy while minimising toxicity. Prospecti...
- Biology
BACKGROUND: Nonfermenting Gram-negative bacilli other than Pseudomonas and Acinetobacter species are increasingly recognized as opportunistic pathogens in pediatric populations, yet their epidemiology and antimicrobial resistance remain poorly defined. METHODS: We conducted a mul...
- Health & MedicineOpen access
Pancreatic panniculitis as the sole manifestation of pancreatic ductal adenocarcinoma: a case report
Pancreatic panniculitis is a rare form of lobular panniculitis characterized by subcutaneous fat necrosis occurring at cutaneous sites distant from the pancreas. It is most often associated with pancreatitis, while pancreatic malignancies — dominated by acinar cell carcinoma — re...