Hôpital Farhat Hached

Gluten-free diet adherence and associated practical, socioeconomic, and psychological factors among Tunisian adults with self-reported celiac disease: a cross-sectional study

Background Maintaining a gluten-free diet (GFD) is essential in celiac disease, but North African adherence data are limited. We described adherence classifications and explored associated factors in a selected Tunisian online sample. Methods The survey was conducted from 25 June...

A silent killer mimicking appendicitis: primary signet-ring cell carcinoma of the colon in a child—case report and literature review

Introduction Signet-ring cell carcinoma (SRCC) of the colon is extremely rare and highly aggressive in children. Presentation as an acute abdomen is uncommon and may mimic acute appendicitis, delaying diagnosis. Case presentation A 10-year-old boy with no relevant personal or fam...

Quran Memorization as a Naturalistic Neurocognitive Training Paradigm: A Quality-Weighted Evidence Synthesis in Student Populations

Aim We aimed to quantitatively synthesize observational evidence on the association between memorization ( Hifz ) and cognitive and mental health outcomes in students, using a quality-weighted evidence synthesis approach. Method For observational studies published between 2005 an...

Workflow management systems and reproducible pipelines for Plasmodium falciparum genomic surveillance: tools, design principles and infrastructure challenges

Genomic data are increasingly leveraged to enable malaria genomic surveillance, with many teams now generating Plasmodium falciparum sequence data for routine analysis. However, downstream analysis remains dependent on ad-hoc scripts and local infrastructure. This reliance limits...

Fatal toxic epidermal necrolysis induced by high-dose methotrexate in T-cell acute lymphoblastic leukemia

IntroductionHigh-dose methotrexate (HD-MTX) is a cornerstone in the treatment of acute lymphoblastic leukemia but carries a risk of severe toxicity. Toxic epidermal necrolysis (TEN) is a rare life-threatening adverse reaction.Case reportWe report the case of a 15-year-old male wi...