Henan Provincial People's Hospital

Joint effects and mediating mechanisms of body roundness index and biological aging on the risk of incident cardiovascular disease: a nationally representative prospective cohort study

Body roundness index (BRI) and biological aging are critical drivers of cardiovascular disease (CVD). However, their joint pathogenic effects and underlying mechanisms in the development of CVD remain elusive. This study aims to investigate the independent and joint effects of BR...

Research progress on multi-mechanism analysis and protection strategies of ovarian aging and fertility decline

Age-related fertility decline is an increasingly important challenge in reproductive medicine, driven largely by progressive ovarian aging. The aging ovary undergoes functional deterioration characterized by reduced ovarian reserve and declining oocyte quality, ultimately limitin...

Tranexamic acid in primary total knee arthroplasty: a systematic review and meta-analysis of blood loss, transfusion, and deep vein thrombosis

Tranexamic acid (TXA) has been widely used in primary total knee arthroplasty (TKA) to reduce perioperative blood loss, but the pooled evidence regarding blood loss, transfusion, and deep vein thrombosis (DVT) remains to be further clarified. The purpose of this meta-analysis was...

Neutrophil percentage-to-albumin ratio is associated with in-hospital mortality in patients with acute aortic dissection: a multicenter retrospective cohort study

Early risk stratification remains challenging in patients with acute aortic dissection (AAD). This study aims to evaluate the prognostic value of neutrophil percentage-to-albumin ratio (NPAR) for in-hospital mortality in patients with acute aortic dissection. We performed a multi...