Hacettepe University Hospital

Association between perioperative acute kidney injury and in-hospital mortality in patients aged 80 years and older undergoing hemiarthroplasty for femoral neck fractures: a retrospective cohort study

Early mortality remains a major concern in very elderly patients undergoing surgery for femoral neck fractures. Although frailty and comorbidity indices are commonly used for perioperative risk assessment, the prognostic significance of perioperative renal dysfunction in this pop...

Guideline-grounded retrieval versus unconfigured generation in obstructive sleep apnea: a pilot comparison of notebookLM and ChatGPT for AASM v3.0 PSG scoring-rule questions

Large language models (LLMs) are increasingly used in sleep medicine, but their reliability for polysomnography (PSG) scoring-rule tasks that require up-to-date guideline knowledge remains uncertain. This pilot study compared response quality when identical AASM v3.0 PSG scoring-...

Stromal THY1 expression is associated with improved survival in low-stroma colorectal cancer: an integrated multi-platform analysis

Abstract Background Colorectal cancer (CRC) remains a global health challenge. The tumor microenvironment (TME) plays an important role in CRC progression, yet the cellular distribution and prognostic significance of stromal THY1 (CD90) remain incompletely understood. Methods We...

Real-world outcomes of second-line therapy in advanced thymic carcinoma: a multicenter Turkish Oncology Group (TOG) study

Abstract Background Thymic carcinoma (TC) is a rare and aggressive malignancy with limited evidence guiding second-line treatment after prior systemic therapy. We evaluated real-world outcomes of second-line systemic therapy in a multicenter cohort. Methods Adults with unresectab...