Institution
Guangdong Medical College
Recent research
- Health & MedicineOpen access
The genetic associations between macrophage polarization-related genes (MPGs) and sepsis remain unclear. This study aimed to identify sepsis-associated MPGs. Based on blood-derived methylation quantitative trait loci (mQTL), expression QTL (eQTL), and protein QTL (pQTL) data for...
- Health & MedicineOpen access
Parents’ knowledge, attitude, and practice toward mouth breathing in children: a mediation analysis
This study aims to assess parents’ knowledge, attitude, and practice (KAP) regarding mouth breathing in children. This multicenter cross-sectional study was conducted from July to October 2024 among parents. A total of 1,966 valid responses were analyzed. Among the children, 1,07...
- Engineering & Technology
Abstract Flexible electronics and wearable devices require hydrogels that integrate high strength, stretchability, adhesion, and stable conductivity. However, conventional polyacrylamide (PAM) hydrogels suffer from poor mechanics, low conductivity, and weak adhesion, limiting the...
- BiologyOpen access
Abstract Postmenopausal osteoporosis is characterized by a disruptive bone‑fat imbalance, yet effective therapies remain limited. Here, for the first time, we link the traditional use of fish maw heat‑treated with clam shell powder (CPFM) to the restoration of bone‑fat balance. U...
- Health & MedicineOpen access
Mefatinib, a novel second-generation epidermal growth factor (EGFR) tyrosine kinase inhibitor that has shown promising antitumor activity in targeting non-small cell lung cancer (NSCLC) with common and uncommon EGFR- activating mutations. In this phase III, randomized, double-bli...
- Health & MedicineOpen access
Altered circulating blood microbiota in unexplained recurrent spontaneous abortion
The etiology of unexplained recurrent spontaneous abortion (URSA) remains poorly understood. Emerging evidence implies that URSA is closely related to dysbiosis of the symbiotic microbiota, while the characteristics of blood microbiome in URSA remain unclear. In the present preli...
- BiologyOpen access
Abstract Major depressive disorder (MDD) is a widespread, recurrent, and severely disabling psychiatric disorder that imposes a heavy global health burden. Although genetic factors contribute to disease risk, growing evidence highlights gene-environment interaction as the core dr...
- Engineering & TechnologyOpen access
To develop an isoniazid-loaded biomimetic mineralized collagen scaffold and assess its biocompatibility, osteogenic capacity, and anti-tuberculosis activity. We fabricated a drug-loaded mineralized collagen scaffold from type I collagen using biomimetic mineralization self-assemb...
- Health & MedicineOpen access
Sepsis-associated acute kidney injury (SA-AKI) is a highly heterogeneous syndrome with variable clinical trajectories and outcomes. Conventional staging systems, such as KDIGO, fail to capture this heterogeneity, limiting risk stratification and personalized management. We aimed...
- BiologyOpen access
Magnetotactic bacterial-reprogrammed TCR-macrophages for durable anti-tumor photoimmune therapy
Macrophage have shown great promise in the clinical treatment for head and neck cancer (HNC). However, macrophage therapies confront significant hurdles due to a deficiency of tumor-specific targets and tumor resistance. Herein, we report the development of a magnetotactic bacter...
- Society & EconomicsOpen access
Abstract Background A large number of theoretical reasoning and empirical studies have shown that both parenting style and self-esteem have an impact on the formation of rejection sensitivity, and there may be more complex mechanisms between the above variables. This study aims t...