Georgia State University

Heart failure‐induced reprogramming of salt‐evoked neurovascular coupling in the rat hypothalamus

Abstract Neurovascular coupling (NVC) is essential for matching cerebral blood flow to neuronal activity. While NVC has been extensively studied in the cerebral cortex, far less is known about its regulation in deep brain regions such as the hypothalamus, particularly under patho...

Sex & Gender Science: integrating the social with the biological

Abstract For decades, researchers have largely studied aspects of sex and gender separately; the former as a basic science and the latter as a social construct with real world consequences, including health inequities. In recent years, as our collective understanding of how the b...

Clusters, fingers, and singles: A mechanical landscape of tumor invasion

Abstract Collective invasion is a key mechanism by which tumors disseminate and metastasize, involving coordinated migration of heterogeneous cell populations. Experimental studies have identified specialized leader and follower cells that work together during this process, but t...

Counting twitches: automated mechanomyography of muscle fatigue in healthy adults

Abstract Background Assessing skeletal muscle fatigue is essential for diagnosing neuromuscular impairment, but conventional methods rely on maximal or tetanic contractions that can be impractical or uncomfortable in clinical populations. Surface mechanomyography (MMG) provides a...

Distilling the WhiSCCI: Development of the White Short Critical Consciousness Index

Critical consciousness (CC) describes a system of awareness and action to liberate marginalized communities from oppressive systems. Modern scholarship often portrays CC as a tripartite model featuring an awareness of oppressive systems, the motivation to change them, and the act...

Large-Scale Open Science Simulated Data to Study the Development of Brain and Behavior Relationships: Epidemiologic, Clinical, and Neuroimaging Characteristics

Both brain and behavior undergo considerable changes during adolescence, a time synonymous with the emergence several psychiatric disorders, including mood and psychotic disorders. Multiple studies have explored the interaction between brain and behavior during childhood and adol...

Transferable Optimization Network for Cross-Domain Image Reconstruction

Abstract. We develop a novel transfer learning framework to tackle the challenge of limited training data in image reconstruction problems. The proposed framework consists of two training steps, both of which are formed as bilevel optimizations. In the first step, we train a powe...

Learning Theories Atlas

A visual, interactive atlas of how learning has been theorized. Click any bubble to open its family: six research philosophies at the top, twelve big paradigms beneath, and hundreds of theories, frameworks, methods, principles, and concepts branching out below. Every node opens a...

Learning Theories Atlas

A visual, interactive atlas of how learning has been theorized. Click any bubble to open its family: six research philosophies at the top, twelve big paradigms beneath, and hundreds of theories, frameworks, methods, principles, and concepts branching out below. Every node opens a...

Youth in Detention: Institutional Contexts and Within-Person Change in Psychopathic Traits

Due to many negative effects of institutionalization, adolescents who make contact with the justice system represent a particularly vulnerable population. Justice-involved youth exhibit psychopathic traits at rates higher than the general population. Due to the heterogeneous natu...

Deciphering the evolutionary origin of the enantioselectivity of short-chain dehydrogenases from plants toward 1-borneol

Abstract Enzyme engineering has produced numerous methods to optimize enzymes for biotechnological processes; however, less is known about how natural evolution creates new functionalities. We investigate the evolutionary emergence of enantioselectivity in plant borneol dehydroge...

CLASPP: A unified model for predicting post-translational modifications

Abstract Post-Translational Modifications (PTMs) are a fundamental mechanism for regulating cellular pathways and increasing the functional diversity of the proteome. Accurately predicting the PTM types that are likely to occur at a given site in the primary sequence is a key cha...

One Stone Two Birds: Novel Fluorescent Probe ChemistryThat Detects Redox Stress in Cell Culture

Abstract Redox homeostasis is a critical part of physiological processes. Disruption of such homeostasis is associated with various pathological conditions. Tools for studying cellular redox states are important for understanding various biological mechanisms and for the targeted...

When Should Demographics Enter the Prior? Conditional Exchangeability in Bayesian Estimation of Risk Preferences

Hierarchical Bayesian models for the estimation of individual risk preferences typically assume that subjects are unconditionally exchangeable: prior to seeing any data, every subject is treated as a draw from a common population distribution. We examine the consequences of relax...

Highly Repeatable Fibrous Crack‐Based Strain Sensor for Multichannel Continuous Tremor Monitoring in Parkinson's Disease and Essential Tremor

ABSTRACT Objective measurement of tremors is important for assessing the severity and preventing misdiagnosis of Parkinson's disease (PD). To address this demand, this study presents a multichannel, wireless, patch‐type tremor monitoring system that integrates a high‐repeatable f...

The influence of input modality and listening anxiety on young learners’ second language listeningcomprehension

Abstract Despite the crucial role of listening in second language (L2) learning, understanding the impact of different listening modalities remains an ongoing challenge. This issue has become even more relevant as language learning increasingly takes place in digital environments...