George Washington University

Earliest simultaneous multi-color optical observations of GRB 230328B: from 41 seconds to the host-galaxy identification

Abstract We present a multiwavelength study of the long-duration gamma-ray burst GRB 230328B, combining prompt γ-ray observations with exceptionally early simultaneous optical photometry and extensive X-ray, radio, and host-galaxy follow-up. NUTTELA-TAO began simultaneous g′r′i′...

Gaps in Clinical Guidelines and Recommendations for Preexposure Prophylaxis and Postexposure Prophylaxis Screening to Prevent HIV Transmission in the United States

Despite the availability of preexposure prophylaxis (PrEP) and postexposure prophylaxis (PEP) for the prevention of HIV transmission, 30 000 new cases of HIV are reported every year in the United States. Barriers to PrEP and PEP use are multifactorial and include clinician misinf...

Dispatch or Hold? An Inverse Optimization and Reinforcement Learning Approach for Multiobjective On-Demand Delivery

In large-scale on-demand food delivery systems, dynamic order dispatching needs to balance immediate dispatch and order holding amid competing objectives, including delivery efficiency, service timeliness, and courier utilization. Holding certain orders for future consolidation m...

Conditional Deep Learning for Urban Origin–Destination (OD) Matrix Estimation Under Varying Connected-Vehicle Penetration

Connected vehicles and vehicle-to-everything (V2X) communication create new opportunities for estimating urban origin–destination (OD) demand from continuously collected mobility data. However, in realistic deployment conditions, only a fraction of vehicles may be connected, maki...

BeyondFreeze Concentration:Interfacial ProcessesShape Cr(VI) Reduction by Organic Acids in Frozen Systems

Abstract Ice-phase Cr(VI) reduction is commonly attributed to freeze concentration and proton enrichment, implicitly assuming solution-like reaction mechanisms. However, this study reveals that interfacial processes serve as a critical complement to freeze concentration and stron...

The hematology workforce in the United States: past, present, and strategies for the future

From 2017-2021, the American Society of Hematology (ASH) completed the largest study ever conducted of the hematology workforce in the United States (US). The study highlighted a deficit in the classical hematology (CH) workforce: despite very high CH clinical volumes encountered...

Characterization of Anticholinergic Medication Use and Its Associations With Everyday Memory Problems and Cognitive Decline in Autistic Adults With Higher Support Needs

ABSTRACT Among older adults in the general population, medications with anticholinergic (AC) effects are associated with declines in cognitive functioning and with dementia and Alzheimer's disease. Autistic people have high rates of co‐occurring medical conditions and polypharmac...

Ethical implications of screening for loneliness in primary care when intervention capacity is limited

Abstract Background Loneliness has emerged as a clinically significant health concern, prompting growing interest in systematic screening in care settings. However, the ethical justification for such screening remains uncertain when intervention capacity is limited or inequitably...

Practitioner's Pulse: A Content Analysis Approach for Examining Prevalent Topics in HRD Practitioner Periodicals

ABSTRACT This article presents a methodological approach for analyzing Human Resource Development (HRD) practitioner perspectives through a content analysis (CA) of periodicals. While CA has been applied to academic literature, its application to practitioner periodicals represen...

Disability-Related Differences in Substance Use Among U.S. Young Adults

BACKGROUND: People with (vs without) disabilities may be at greater risk for substance use, but limited research has explored the use of various substances among people with disabilities. This study examined differences in substance use among U.S. young adults with versus without...

Beyond Beneficence: Commerce and Interaction in Relation to Kant’s Formula of Humanity

In the Groundwork of the Metaphysics of Morals , Kant names beneficence, or promotion of another’s happiness, as the way we attain “positive” agreement with the humanity in another person (GMS 4:430). I argue, however, that beneficence is not the only way, or necessarily the pref...

AspirationPatch Proteomics Enables CE–ESI–MSProteotyping of Identified Single Neurons in Intact Brain Tissue

Abstract Direct proteome analysis of identified neurons in intact brain tissue remains limited by the difficulty of recovering intracellular material while preserving native tissue context and avoiding physical extraction of the intact soma. Here, we establish aspiration patch pr...

Social cues on stone tools outweigh raw material properties in wild primates

1. Abstract The ability to select appropriate tool material enabled early hominins access to new resources and environments. The underlying mechanisms driving tool selection effectively remain unknown. Observations of extant primates have demonstrated strong selectivity for speci...

Derivation of Pediatric Emergency Preparedness Checklist for Urgent Care Centers

OBJECTIVES To develop a consensus-based pediatric emergency preparedness checklist tailored for urgent care centers, addressing policies, procedures, personnel, equipment, and medications necessary to stabilize critically ill or injured children prior to transfer. METHODS A modif...