General Hospital of Athens G. Genimatas

Evaluating early systemic therapies in the neoadjuvant setting for the treatment of urological cancers

INTRODUCTION: Neoadjuvant systemic therapy represents an evolving cornerstone in the multidisciplinary management of urological malignancies. While cisplatin-based neoadjuvant chemotherapy historically represented the sole standard of care for muscle-invasive bladder cancer, nove...

Lipoprotein and apolipoprotein levels in age-related macular degeneration: A meta-analysis

Purpose Drusen, the hallmark of AMD, are lipoprotein-rich particles. However, the role of systemic lipid metabolism in their formation remains controversial. This meta-analysis explored the association between ApoA1, ApoA2, ApoB and Lp(a) serum levels and AMD. Methods We systemat...

Effects of SMILE on intraocular pressure and corneal biomechanics: a systematic review and meta-analysis

Abstract Purpose Small incision lenticule extraction (SMILE) is a popular flapless refractive procedure for myopia and myopic astigmatism, although postoperative corneal biomechanical changes may affect intraocular pressure measurements and glaucoma assessment. This systematic re...

Rapid Corneal Melt From Dual Acanthamoeba and Pseudomonas aeruginosa Keratitis

Abstract: A 27-year-old woman, contact lens wearer, visited the ophthalmology department with acute ocular pain, photophobia, and a reduction in visual acuity. A slit-lamp examination was performed, and the signs were a central corneal ulcer along with corneal thinning, hypopyon,...