Institution
Geisinger Health System
Recent research
- Health & Medicine
Trends in annual medication possession in older adults with type 2 diabetes
BACKGROUND: Older adults (≥65 years) make up a substantial portion of individuals with type 2 diabetes (T2D) and frequently experience multimorbidity requiring complex, costly medication regimens. Cost-related nonadherence is prevalent in this population because of fixed incomes,...
- Health & Medicine
BACKGROUND AND OBJECTIVES: Aspiration catheters are an integral component of mechanical thrombectomy for acute ischemic stroke (AIS). Following early series demonstrating increasing procedural efficiency and improved outcomes with use of large-bore (LB) aspiration catheters, ther...
- BiologyOpen access
Cross-biobank comparison of ASCVD heritability and genetic correlation
Abstract Estimates of SNP-based heritability for atherosclerotic cardiovascular disease (ASCVD) vary widely across populations, complicating interpretation of genetic architecture. We compared SNP-based heritability and cross-cohort genetic correlation for ASCVD and its nested su...
- Health & Medicine
Background The Brain Trauma Foundation’s guidelines specifically highlight the need to determine optimal triage destination for moderate traumatic brain injury (modTBI) patients, particularly in rural settings where Level I trauma centers may be geographically distant. Methods Re...
- Health & MedicineOpen access
Background: Population-level patterns in the real-world use of initial treatment combinations for glioblastoma (GBM) remain poorly characterized. Materials and Methods: We assessed temporal trends in treatment and survival among patients with GBM in the SEER registry. Guideline-c...
- Health & MedicineOpen access
Abstract Background Anterior clinoid meningiomas (ACM) and tuberculum sella meningiomas (TSM) are anterior skull base tumors that commonly cause visual deterioration. The supraorbital keyhole approach may be used to resect these tumors but is limited by restricted intraoperative...