Fujian University of Traditional Chinese Medicine

Acupuncture and Moxibustion for Neck Pain: A Clinical Practice Guideline

ABSTRACT Background Neck pain (NP) is a leading cause of disability worldwide. Pharmacological treatments often provide limited benefits and may be associated with adverse effects, highlighting the need for effective non‐pharmacological options. Aim To develop evidence‐based reco...

Development and Validation of an Interpretable Machine Learning Model for Osteoporosis Prediction Using Multimodal Musculoskeletal Ultrasound and Clinical Features

Objectives This study aimed to develop and validate an interpretable machine learning model for osteoporosis prediction based on multimodal ultrasound and clinical features. Methods Participants with suspected osteoporosis were enrolled from 2 medical centers. Clinical variables...

Dynamic cardio-renal-metabolic trajectories identify sepsis subphenotypes for individualized management: a cross-population cohort study

Sepsis heterogeneity remains a major barrier to precision medicine. Although cardio-renal-metabolic interactions critically influence outcomes, their dynamic evolution is rarely integrated into clinical phenotyping. We aimed to identify distinct sepsis subphenotypes based on dyna...

Primary pulmonary mucosa-associated lymphoid tissue lymphoma presenting as a right hilar mass

Rationale: Primary pulmonary lymphoma (PPL) is an extremely rare malignant lung tumor that is frequently misdiagnosed as pneumonia or lung cancer due to its atypical radiological and clinical presentation. The rationale of this report is to elucidate the diagnostic value of combi...

Arterial‐Ventricular Coupling Strain Index as an Independent Predictor of 10‐Year ASCVD Risk in Diabetic‐Hypertensive Patients

BACKGROUND AND AIMS: The combination of diabetes mellitus and hypertension significantly increases the risk of cardiovascular diseases (CVD). This study aimed to evaluate the association between ventricular-arterial coupling and the 10-year atherosclerotic cardiovascular disease...

Ilexoside K Ameliorates Atherosclerosis by Suppressing CD72 hi Macrophages and Blocking CXCL12–CXCR4 Axis to Inhibit Endothelial Pyroptosis

ABSTRACT Atherosclerotic cardiovascular disease (ASCVD) remains the leading global cause of mortality, with substantial residual inflammatory risk persisting despite statin therapy. We identify a c‐Rel‐driven CD72 hi macrophage subset markedly enriched in human and murine atheros...

Cancer and Hypertension: Shared Mechanisms, Treatment Interactions, and Clinical Management

ABSTRACT Cancer and hypertension (HTN) frequently coexist, and their relationship is increasingly recognized as a clinically relevant intersection between oncology and cardiovascular medicine. However, the extent to which this association reflects shared risk factors, common biol...

Treatment disruption and psychological distress among hemophilia patients during the COVID-19 pandemic: the role of healthcare accessibility

The strict zero-COVID policies in China, lasting from early 2020 to late 2022, posed unique challenges to chronic disease management. While the pandemic’s mental health impact is well-documented, evidence regarding patients with hemophilia remains limited. This study aimed to ass...

Dietary patterns and depression: a comprehensive review of associations, moderating factors, and underlying mechanisms

Depression is a widespread and multifaceted mental health disorder, shaped by genetic susceptibility, neurobiological dysfunction, and environmental stressors, which pose challenges for effective treatment. Emerging evidence suggests that diet plays a significant role in the occu...

Nonlinear association between sleep duration and depressive symptoms among US adults with chronic low back pain: Evidence from NHANES 2009–2010

Background Depressive symptoms are common among individuals with chronic low back pain (CLBP) and are associated with poorer treatment outcomes. Although sleep problems are frequently reported in this population, the dose-response association between sleep duration and depressive...

Triglyceride-glucose-sarcopenia index and risk of cardiovascular diseases in multinational prospective cohorts

Abstract Background Muscle tissue dictates insulin-driven glucose uptake; muscle dysfunction paired with insulin resistance can trigger a compound cardiometabolic failure. However, whether this dual pathology confers incremental long-term cardiovascular risk stratification is yet...

Effects of self-acupressure on the fatigue-sleep disturbance-depression symptom cluster in breast cancer survivors: a phase III randomised controlled trial

PURPOSE: To explore the effectiveness and safety of self-acupressure intervention on the fatigue-sleep disturbance-depression symptom cluster (FSDSC) among breast cancer (BC) survivors and to explore within-trial costs associated with the intervention. METHODS: Eligible participa...

The complete chloroplast genome sequence of Elatostema involucratum

Elatostema involucratum Franch. & Sav, a perennial herb in the genus Elatostema (family Urticaceae), has significant medicinal value. Here, we report the complete chloroplast genome of E. involucratum for the first time, assembled using high-throughput sequencing. The chloroplast...

Methyl indole-3-acetate contributes to strain-specific anti-inflammatory effects of Lactiplantibacillus plantarum

Lactiplantibacillus plantarum is a widely recognized probiotic with anti-inflammatory potential, yet its efficacy varies among strains and the underlying determinants remain poorly defined. Here, we identify methyl indole-3-acetate (MIA), a previously uncharacterized microbial me...

Predictive value of perioperative hypothermia for postoperative muscular calf vein thrombosis after total knee arthroplasty: a retrospective cohort study

Abstract Objective To investigate the association between perioperative hypothermia and postoperative muscular calf vein thrombosis (MCVT) in patients undergoing total knee arthroplasty (TKA), and to evaluate the predictive performance of perioperative core temperature indicators...

A CCCTC-binding factor (CTCF)-fatty acid desaturase 1 (FADS1) axis regulates oncogenic energy metabolism in hepatocellular carcinoma

CCCTC-binding factor (CTCF) is a highly conserved DNA-binding protein crucial for 3D genome organization and gene regulation. Previous studies have shown that CTCF overexpression in hepatocellular carcinoma (HCC) is associated with poor prognosis. This study aimed to elucidate th...

Zinc Fertilization Mitigates Boron Toxicity in Citrus: Plant Growth, Tissue Mineral Composition and Antioxidant Enzyme Activity

Boron (B) toxicity is a common issue in Citrus production regions worldwide. Zinc (Zn) has been reported to mitigate B toxicity in plants, but the underlying regulatory mechanisms remain poorly elucidated in Citrus. In this study, ’Sweet orange’ (Citrus sinensis) and ’Sour pomelo...

Pesticide Residues, Gut Microbiota, and Gastrointestinal Outcomes: A Scoping Review of Human Evidence

ABSTRACT Vegetables anchor healthy‐diet recommendations yet are the principal nonoccupational route by which residues of organophosphate (OP), pyrethroid, neonicotinoid, organochlorine (OC), and glyphosate herbicide enter the diet, with the gut microbiota a plausible mediator lin...

Remote electroacupuncture conditioning protects the heart via fine-tuning the dual role of the SDF-1α/CXCR4 axis in myocardial ischemia–reperfusion injury

BACKGROUND: Remote electroacupuncture (EA) conditioning on forearm protects against myocardial ischemia-reperfusion injury (MIRI). However, the cardioprotective mechanisms of RIC have not been fully elucidated. This study aimed to investigate whether EA could balance the pro-surv...

ATF4 and FGFR4 cooperatively support thyroid cancer progression and CAF-associated tumor-promoting features

Aggressive thyroid cancer remains difficult to treat, partly because molecular programs linking malignant behavior to cancer-associated fibroblast (CAF)-related support are incompletely defined. This study investigated whether ATF4 and FGFR4 cooperate in thyroid cancer cells and...