Freie Universität Berlin

Fast post-ploughing recovery of traditionally managed semi-natural mountain grasslands in the Romanian Carpathians

Mountain hay meadows are among the most species-rich grassland habitats in Europe, yet many have been historically ploughed and later re-established under traditional management. We examined the legacy effects of past ploughing on plant diversity, vegetation composition, and soil...

Diorganotelluride···N Chalcogen Bonds: Analysis and Tuning of Two σ‐Holes

Organotellurium(II) compounds contain two σ‐holes that may be fine‐tuned through substituents. This work investigates the structural chemistry of two new chalcogen bond (ChB) aggregates of organotellurium(II) compounds and the strong bases 1,4‐diazabicyclo[2.2.2]octane (DABCO) an...

Outcomes in JIA have greatly improved, but we can still do better

Abstract Outcomes for children and adolescents with juvenile idiopathic arthritis (JIA) have improved substantially over the past two decades, driven by biologic and targeted synthetic DMARDs, treat-to-target strategies with regular standardized assessments, and multidisciplinary...

Multimodal fertility cues in chimpanzees: how body odours complement sexual swellings

Abstract To attract mating partners, female mammals communicate their reproductive status through one or multiple sensory modalities, providing redundant or complementary information. Chimpanzees ( Pan troglodytes ) are an excellent model for studying multimodal communication. Ex...

Narratives as Separating Equilibria: On the Origins of the Ukraine War

NATO enlargement and Russian occupation of Crimea marked crucial turning points in the process that eventually resulted in the Ukraine war. According to one narrative, that Russian move was part of a plan to re-establish dominion over Eastern Europe. According to a rival view, it...

Motion Anisotropy of Individual, Unconfined Rod-Like-Shaped Salmonella Typhimurium Bacteria

Abstract With the continuous advancement of microscopic imaging techniques, the motion of micro- and nanosized particles can be followed with increasing spatial and temporal accuracy. Analyzing the tracks of single particles enables one to address a broad range of scientific ques...

Shaping light in 3D for direct asymmetric photochemistry: a 1000-fold enantioselectivity enhancement

Abstract Shaping electronic motion with tailored light enables unprecedented control over matter: from realising topological states in quantum materials to steering chemical reactions along specific pathways. Yet, despite the vital roles of molecular chirality across nature, stan...

Bacterial Pneumonia in Horses: Insights from a 10-Year European Single-Centre Retrospective Study

Bacterial pneumonia in horses typically occurs secondary to predisposing factors that compromise defence mechanisms. This 10-year retrospective study evaluated bacterial pneumonia in 81 horses treated at the equine clinic of Freie Universität Berlin from January 2015 to December...

Clinical Urgency of After-Hours Presentations of Dogs and Cats to a Private Small-Animal Practice in Germany: A Retrospective Study of 4579 Visits

This descriptive study aimed to assess the urgency of after-hours emergency visits in a small-animal practice using a structured triage system, and to characterize the associated presenting conditions and treatments. Medical records of 3189 dog and 1390 cat visits presented betwe...

Classification of Seasonal Allergic Rhinitis Patients by Prospective Patient‐Recorded Symptoms: The @ IT .2020 Project

BACKGROUND: Seasonal allergic rhinitis (SAR) has been so far classified according to frequency and severity by retrospective information based on the ARIA (Allergic Rhinitis and its Impact on Asthma) classification. Electronic symptom diaries (e-Diaries) are feasible tools to col...

Search for neural correlates of object and panorama learning in mushroom body extrinsic neurons of bumblebees

A laboratory-based setup was developed that allowed us to train bumblebees to a rewarding object (local cue) in the context of a panorama and simultaneously to record extracellularly the neural activity of units interpreted as mushroom body extrinsic neurons (MBENs). This setting...

Volumetric reference data of the orbit: a deep learning MRI analysis in the German national cohort

Abstract Manual segmentation of orbital magnetic resonance imaging (MRI) is labor-intensive, hindering large-scale morphometric studies. To overcome this, we developed a fully automated deep learning pipeline to segment orbital MRIs and establish age- and sex-stratified normative...

Tracking Variability in Atmospheric, Oceanic, and Riverine Inputs to the Iberian Margin Over the Last 250 kyr

Abstract The Iberian Margin provides an exceptional archive of climate variability due to its high sedimentation rates. However, uncertainties persist regarding the provenance of terrigenous detrital sediments on the Iberian Margin, and the climate‐driven changes in their source...

Carbon and nitrogen availability affects biofilm growth and morphology of the extremotolerant fungus Knufia petricola

ABSTRACT Rock-inhabiting fungi thrive in subaerial oligotrophic environments, such as desert rocks, solar panels, and marble monuments, where organic carbon and nitrogen are scarce. We tested whether the rock-inhabiting fungus Knufia petricola showed a preference regarding nitrog...

Tissue and Cerebral Biofluid Remodelling of tRNA-Derived Small RNA Signatures in Experimental and Human Epilepsy

Small noncoding RNAs are increasingly recognized as important regulators of gene expression in brain diseases including epilepsy. tRNA-derived small RNAs (tsRNAs) including tRNA fragments (tRFs) and tRNA halves (tiRNAs) are emerging as stable and regulated RNA species which respo...

miR-155-5p drives coordinated tumor and macrophage reprogramming across multiple cancer entities

Abstract Background T cell-based immunotherapies have improved cancer treatment, however their efficacy is frequently limited by tumor-intrinsic resistance mechanisms and by the immune suppressive tumor microenvironment, counteracting tumor specific immune responses through impai...

When politics shapes technology adoption: a cross-national study of chatbot acceptance

Existing literature on chatbot acceptance has largely relied on the Technology Acceptance Model (TAM) or Unified Theory of Acceptance and Use of Technology (UTAUT), often neglecting the broader political, cultural, and attitudinal factors that shape user perceptions. Drawing on a...

An ab initio foundation model of wavefunctions that accurately describes chemical bond breaking

Abstract Reliable description of bond breaking remains a major challenge for quantum chemistry due to the multireference character of the electronic structure in dissociating species. Multireference methods in particular suffer from large computational cost, which under the norma...

Implementing methane dynamics into the LPJmL6 model

Abstract. We extend the Dynamic Global Vegetation Model LPJmL to version 6.0 by explicitly representing methane (CH4) dynamics within the coupled carbon–nitrogen–water system. The implementation (i) prognoses water-table depth and wetland extent using a CTI–TOPMODEL framework, (i...

Ketamine’s impact on rumination-related brain dynamics: insights from a randomized controlled fMRI trial

Abstract Rumination has been associated with aberrant dynamics of a coactivation pattern (CAP) comprising the default mode (DMN) and frontoparietal (FPN) networks. Ketamine exerts rapid antidepressant effects and may influence these dynamics via glutamatergic mechanisms. In a ran...