Institution
Florida College
Recent research
- Health & Medicine
ABSTRACT We hereby describe a new sonographic sign, the cardiac “flip” sign, to help in the prenatal detection of a right sided aortic arch with a right sided ductus arteriosus. This sign depends on pattern recognition where the sonologist/sonographer needs to obtain a cardiac sw...
- Climate & EnvironmentOpen access
Likelihood‐Based Inference With Separable Correlation Matrices
ABSTRACT This paper proposes methods for likelihood‐based inference in multivariate linear regressions when the correlation matrix of the responses is separable; that is, it has a Kronecker product structure, but the variances are unrestricted. The methods are enabled by a block‐...
- BiologyOpen access
Baseline Serum Metabolites as Predictors of Teplizumab Response in Individuals With Type 1 Diabetes
Abstract Aims/hypothesis Immunotherapies such as Teplizumab can preserve residual beta cell function in individuals with newly diagnosed type 1 diabetes (T1D), but treatment response is variable. Currently, no biomarker exists to identify individuals most likely to benefit from i...
- Health & MedicineOpen access
Menopause represents a major neuroendocrine transition characterized by substantial hormonal, metabolic, vascular, and inflammatory changes that may increase vulnerability to cognitive decline and neurodegenerative disease. Declining estrogen levels during the menopausal transiti...
- Health & MedicineOpen access
Abstract Amyloid aggregation into polymorphic fibrils is central to many neurodegenerative and systemic diseases, yet the physical origins of fibril polymorphism and time-dependent morphological evolution remain unclear. Because mature fibril morphologies are separated by high en...
- Materials & Energy
Pushing theLimits of Ultrasmall PbSe Magic-SizedClusters
Abstract Ultrasmall PbSe magic-sized clusters (MSCs) are important for probing the nucleation of nanocrystals and their optical properties under strong quantum confinement. The smallest PbSe MSC observed so far in the growth sequence has an absorption maximum at 625 nm. Here, we...
- Health & Medicine
Abstract Marine cyanobacteria are a rich source of diverse bioactive natural products, targeting proteins involved in many diseases. Here, we combined metagenomic analysis to enhance the structure elucidation process of two new cyclodepsipeptides named dapalides D (1) and E (2) f...
- Health & Medicine
Data sharing not applicable to this article as no datasets were generated or analysed during the current study.
- Health & Medicine
ABSTRACT Objectives Rhabdomyosarcoma represents the most common paediatric soft tissue sarcoma, with 40% occurring in the head and neck region. Given that survival rates now reach 80%, minimising late adverse effects, particularly dental developmental complications, has become a...
- Society & EconomicsOpen access
How High is the Bar? Pension Fund Benchmark Choices in Real Assets
Abstract This paper examines how defined benefit pension funds select and revise performance benchmarks for real assets, including private real estate, listed REITs, infrastructure, commodities, and natural resources. Using data from CEM Benchmarking, we document substantial hete...
- Biology
Evaluating Mechanical-EmbeddingML/MM for PredictingMutation Effects in Chorismate Mutase Catalysis
Abstract Predicting how mutations alter enzyme catalysis remains a central challenge in enzymology and enzyme engineering. Although quantum mechanics/molecular mechanics (QM/MM) simulations can in principle compute the activation free energy associated with enzymatic reactions, t...
- Biology
Investigating substituted phenylacetamide ligands in the D4R extended binding pocket.
R binding pocket.