First Hospital of Jilin University

Behçet disease with left superficial femoral artery pseudoaneurysm: a case report

Background: Behçet’s disease (BD) is a systemic vasculitis secondary to connective tissue disease of unknown etiology. The prevalence of BD varies geographically, being highest along the ancient Silk Road, including in the Middle East and East Asia. BD may involve the gastrointes...

Association Between Cognitively Stimulating Activities and Cognitive Function in Older Adults Living in Residential Care Homes

OBJECTIVE: To examine the relationship between cognitively stimulating activities and cognitive function among older adults in residential care homes. METHODS: A convenience sampling method was used to recruit older adults from three residential care homes in East China. Data wer...

CACA guidelines for the management of adult cancer pain

Abstract Cancer pain, one of the most prevalent and distressing symptoms in cancer patients, is closely associated with cancer diagnosis, therapeutic interventions, quality of life, and survival outcomes. Effective cancer pain management requires multidisciplinary collaborative a...

Transthoracic echocardiography as a predictor of spinal anesthesia-induced hypotension in cesarean section: a prospective observational study

Spinal anesthesia-induced hypotension (SAIH) is a common complication during cesarean delivery and is closely associated with maternal intravascular volume status. However, reliable real-time assessment of volume changes remains challenging. This study aimed to evaluate whether t...

Clinical utility of molecular residual disease detection in early-stage resected EGFR-mutated non-small cell lung cancer

Molecular residual disease (MRD), detected through circulating tumor DNA, has emerged as a promising biomarker for surveillance in patients with early-stage non-small cell lung cancer (NSCLC) following curative-intent resection. Here we report the MRD analysis from the phase 3 EV...

Randomized phase 2 trial of a PARP inhibitor TSL-1502 in germline BRCA-mutated, HER2-negative locally advanced/metastatic breast cancer

Glucuronide prodrug strategies may enhance target specificity and reduce the toxicity of PARP inhibitors, but no clinical evaluation has been performed. We evaluated TSL-1502, a novel glucuronide prodrug of a PARP inhibitor, in a randomized, open-label, phase 2 study at 28 sites...

Bioinspired MXene-BasedFlexible and Degradable Membranesfor High-Performance Electromagnetic Shielding

Abstract Wearable shielding electronic skin is highly desirable for protecting humans from electromagnetic radiation. However, conventional wearable electromagnetic interference (EMI) shielding materials still encounter major challenges in simultaneously achieving high shielding...