Federal Medical Centre

Comparative predictive performance of insulin resistance surrogates (TyG and TyG-BMI) and lipid indices for cardiometabolic risk in prehypertensive adults

Abstract Background Prehypertension is the initial stage of the risk pathway of CVD, which commonly associates with hidden metabolic derangements such as insulin resistance and dyslipidemia. In the clinical setting, convenient, inexpensive predictors for early screening are requi...

Hydroxybenzoate-based hits from methanolic leaf fraction of Ficus exasperata Vahl: integrative biochemical, molecular, and computational discovery against bisphenol toxicity

Bisphenol A (BPA) toxicity remains a global health concern, with exposure risks exacerbated in Africa due to limited regulatory enforcement and public awareness. Plant-derived bioactive compounds offer a cost-effective strategy to mitigate BPA toxicity. Here, we integrated bioche...