Federal Medical Centre

Oxidative Stress Burden in Paediatric Sickle Cell Anaemia: Effects of Hydroxyurea Therapy, Disease Severity, and Socioeconomic Factors

Background: Oxidative stress plays a central role in the pathophysiology of sickle cell anaemia (SCA), contributing to haemolysis, endothelial dysfunction, and disease complications.Hydroxyurea (HU), the main disease-modifying therapy for SCA, may influence oxidative balance; how...

Controlling Childhood Obesity in Nigeria: Strategies, Barriers, and Policy Implications from a Systematic Review

Childhood obesity is an increasing public health concern in Nigeria, yet evidence on locally used control strategies and the barriers to implementation remains fragmented. This systematic review examined strategies for controlling childhood obesity in Nigeria and the social, cult...

Design-based spatial modelling of malaria incidence among children in Nigeria using latent Gaussian model

National data on malaria are mostly individual-level datasets, collected through complex survey designs, e.g., Malaria Indicator Survey. However, models on malaria in the literature often use count data at geographical level, and scarcely account for complex survey design. The im...

Correlation of modified Thyroidectomy Difficulty Scale with postoperative outcomes following thyroidectomy for multinodular euthyroid goiters in a tertiary hospital, southwest Nigeria

ABSTRACT Background: In Nigeria, many patients present late with large goiter with attendant intraoperative challenges. Complications following thyroidectomy can sometimes be life-threatening or may be associated with significant morbidity. The ability to intraoperatively identif...

Socio-demographic characteristics and awareness of risk factors of severe acute malnutrition among parents of children admitted in stabilization centres in Northern Nigeria: A multi-centre observational study

Objectives: The study aims to determine socio-demographic characteristics and assess awareness of risk factors of severe acute malnutrition (SAM) among parents of children admitted to stabilisation centres in Northern Nigeria. Material and Methods: A descriptive cross-sectional s...

Determinants of adverse drug reaction reporting for antimalarial medicines: a mixed-methods study among healthcare workers in ogun State Southwest Nigeria

Spontaneous adverse drug reaction (ADR) reporting is central to pharmacovigilance, yet underreporting remains common in malaria-endemic low- and middle-income countries (LMICs). This study examined determinants of ADR reporting among healthcare workers involved in malaria case ma...

Pineoblastoma in a 5-Year-Old Male: A Case Report and Review of Literature

Abstract Pineoblastoma (PB) is a rare malignant embryonal tumour arising from the pineal gland. It commonly affects the paediatric age group with a slight male predilection. The typical clinical features include symptoms and signs of raised intracranial pressure, but extracranial...

HPV vaccine knowledge, attitude and practice among medical doctors in Nigeria

Doctors play a key role in providing health information, and their recommendation strongly influences HPV vaccine uptake. This study assessed knowledge, attitudes, and HPV vaccine recommendation practices among medical doctors in Nigeria. An analytical cross-sectional study was c...