Family Health International 360

Pharmacokinetics of Efavirenz in Pregnancy and Postpartum with and Without First-line Tuberculosis Drugs: Results from IMPAACT P1026s

Efavirenz (EFV) pharmacokinetics (PK) may be influenced by both pregnancy-related physiological changes and concurrent treatment for drug-sensitive tuberculosis (DS-TB), and intensive 24-h EFV PK data during rifampin (RIF)/ isoniazid (INH) treatment in pregnant women living with...

Unravelling the Enantiomeric Distribution of Key Sandalwood Sesquiterpenoids by Enantioselective Gas Chromatography and Molecular Rotational Resonance

Abstract The enantiomeric distribution of α- and β-santalol in various Santalum and Osyris species of different origins was determined by the combination of enantioselective gas chromatography and chiral tagging molecular rotational resonance spectroscopy, supported by the prepar...

Mechanistic insight into microbial mediated heavy metal uptake and tolerance

Heavy metal (HM) contamination has become a critical threat to the agro-environment, impairing soil fertility, reducing crop productivity, and disrupting ecological balance. It often displays stunted growth, chlorosis, root rot, and ultimately death of plants in severe cases. Due...

Progress towards Onchocerciasis elimination in Senegal’s historical transmission zones, following sustained annual mass drug administration and multilevel surveillance

Onchocerciasis remains a major public health problem in sub-Saharan Africa, despite decades of control efforts. In Senegal, transmission was historically focal but intense along the Gambia and Falémé river basins in the southeast of the country. Building on the legacy of the Onch...